化痰养阴法对精液黏稠度影响与机理研究.pdfVIP

化痰养阴法对精液黏稠度的影响及机理研究 1 周文彬 ，陈德宁，洪志明，黄忠旺，黎杰运 （深圳市中医院，广东 深圳518033 ） 摘要：【目的】观察化痰养阴法治疗精液粘稠度增高（SHV）症的临床疗效并探讨其作用靶点及机制。 【方法】70 例 SHV 症患者随机分为治疗组（G1）和对照组（G2）。G1 组依化痰养阴法服用中药辨证论治， G2 组则口服维生素Ｃ+维生素Ｅ+锌硒宝片，4 周为一疗程，共治疗 3 个疗程。采取计算机辅助精子分析技 术（CASA)分析精液质量，并检测两组治疗前后精浆前列腺特异性抗原、前列腺三项(锌、酸性磷酸酶、柠 檬酸)。【结果】治疗前两组间基线特征均衡性良好(P0.05)，治疗后两组精液粘稠度、精液质量、精浆 前列腺特异性抗原、前列腺三项等各项指标均有所好转，但 G1 组较 G2 组为佳（P0.05）。【结论】中医 化痰养阴法治疗 SHV 有着良好的临床疗效，恢复紊乱的前列腺分泌功能有可能是其作用机制和靶点所在。 关键词：化痰养阴法；精液黏稠度增高症；SHV；中医。 Clinical Observation And Mechanism Research Of Human Semen Hyperviscosity Treated With Transforming Phlegm And Nourishing Yin Zhou Wenbin1 , Chen De’Ning, Hong Zhiming, Huang Zhongwang, Li Jieyun ( Shenzhen TCM Hospital, Guangdong Shenzhen 518033 ) Abstract : 【Objective】To observe clinical efficacy and find the mechanism on human semen hyperviscosity (HSV) treated with Transforming Phlegm And Nourishing Yin. 【Methods】70 cases of HSV were randomized into treatment group and control group, 35 cases in each one. In control group, Vitamin C, vitamin E,XinXiBao Pian were applied. In treatment group，Chinese medicine was prescribed in light of syndrome differentiation and treatment determination to transforming phlegm and nourishing yin. Clinical efficacy wasobserved after treatment in two groups. 【Result】 There was no significant difference in every index among two groups before the trial(P0.05)．At the end of tria1,the levels of Prostate Specific Antigen(PSA),Zinc, Acyl Carrier Protein(ACP), Citric Acid in seminal plasm, and sperm viscosity, semen quality of two groups were better, Indicating significant difference in the comparison among groups(P0.05). 【Conclusions】 Transforming Phlegm And Nourishing Yi has achieved significant clinical efficacy. Restore the disorder of prostate secretory function may be its mechanism and ta