孕妇和其新生儿维生素D营养关系的研究.docVIP

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孕妇和其新生儿维生素D营养关系的研究.doc

  【摘要】 目的 探讨孕妇与新生儿之间维生素D和钙的关系。方法 采用竞争性蛋白结合法(EPBA)对40例正常孕妇及其新生儿血清进行25羟维生素D测定,并同时检测了血清钙。结果 孕妇与其新生儿血清维生素D水平有相关性(r=0.147,P0.01),孕妇血清维生素D水平(19.7±18.24)nmol/L高于新生儿(11.79±12.07)nmol/L。孕妇与其新生儿血清钙水平无相关性,(r=0.110,P0.05),孕妇血清钙水平(2.34±0.11)mmol/L低于新生儿(2.60±0.16)mmol/L。结论 胎儿的维生素D是母体依从性的,而胎儿的钙离子是掠夺性的。孕妇缺钙是绝对的,缺维生素D是相对的。孕妇应重点补钙,适当补维生素D。   women and their newborns   Ma Futian,Ding Xuelei,Liu Xiuping,et al.   Department of Pediatrics,Second Hospital,Hebei Medical University,Shijiazhuang050000.   【Abstract】 Objective To explore the relation between pregnantwomen and their newborns in vitamin D and calˉcium.Methods To determine25-OH vitamin D concentrations by Enzyme-based-Protein-Binding-Assay(EPˉBA)and calcium concentrations in pregnant women blood and their newborns cord blood.Results Serum25-OH vitaˉmin D concentrations in pregnant women and their newborns cord are positively correlated(r=0.417,P0.01).Serum25-OH vitamin D of pregnant women(19.71±18.24nmol/L)are significantly higher than their newborns(11.7±12.07nmol/L,p0.01).Serum calcium are not correlated in pregnant women and their newborns(r=0.110,P0.05).Serum calcium of pregnant women(2.34±0.11mmol/L)are significantly lower than their newborns(2.60±0.16mmol/L,P0.001). Conclusion Vitamin D status of newborns(fetus)is depended on vitamin D status of their mothers.Newborns(fetus)can actively plunder calcium from their mothers.It is emphasized that it is first to pregnant women supplied with calcium and it is second to pregnant women supplied with vitamin D.   Key words pregnant women newborns vitamin D calcium   为了保证胎儿骨骼系统的正常发育,母体妊娠期间必须不断向胎儿供应维生素D和钙等营养物质,因此,孕妇及其新生儿的维生素D或钙营养一直是人们关注的问题。孕妇补充维生素D、钙剂已是高度自觉、主动实施的过程,不再是医嘱行为。通过孕妇补充维生素D、钙剂,降低了先天性佝偻病的发病率,使孕妇的身体更加健康。但维生素D、钙剂相对人体而言,并非多多益善,对孕妇更是如此。如何使孕妇维生素D、钙剂更加科学、合理,是从事母婴保健工作者始终关心的问题。基于此,本研究对孕妇及其新生儿血清25羟维生素D和钙进行检测,目的在于在以前许多研究的基础上,重新审视孕妇与新生儿之间维生素D、钙的关系,为孕妇维生素D和钙的补充提供科学的理论基础。   1 资料与方法   1.1 一般资料 2001年7月中旬~2001年8月中旬在山西省泽州市妇幼院妇产科分娩的40例孕妇及其新生儿为研究对象。40例孕妇年龄为21~33岁,身高(157.68±5.29)cm,

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