胆管癌术后长期生存的相关因素.pdfVIP

The American Journal of Surgery 181 (2001) 507–511 Scientific papers Predictive factors for long-term survival in patients with intrahepatic cholangiocarcinoma a, a a Tsutomu Isa, M.D. *, Toshiomi Kusano, M.D. , Hideaki Shimoji, M.D. , Yoshitaka Takeshima, M.D.a a b , Yoshihiro Muto, M.D. , Masato Furukawa, M.D. aFirst Department of Surgery, Ryukyu University School of Medicine, 207 Uehara, Nishihara-cho, Okinawa 903-0125, Japan bDepartment of Surgery, Nagasaki Chuo National Hospital, Nagasaki, Japan Manuscript received August 22, 2000; revised manuscript January 15, 2001 Abstract Background: In order to elucidate the predictive factors for long-term survival in patients with intrahepatic cholangiocarcinoma (ICC), we evaluated 7 patients who survived for more than 5 years (5-year survivors). Methods: We examined the clinicopathologic and biologic factors of the 5-year survivors, and these findings were then compared with those in 20 patients who died within 5 years after surgery (control group). Results: In the 5-year survivors, the gross appearance of the tumors included a mass-forming (MF) type in 5 cases, an intraductal growth (IG) type in 1, and another type (microcarcinoma with hepatolithiasis) in 1. No case demonstrated a periductal infiltrating (PI) type. Except for 1 case with an IG type tumor, no lymph node metastasis was seen in any patients. All of the 5-year survivors were classified from stage I to III, and all also