孕妇血清风疹病毒抗体IgM检测的临床意义_夏秀玲.pdf

2008 12 3 36 C h ina P rac M ed, Dec 2008, Vol. 3, No. 36 19 IgM 夏秀玲 IgM ( ELISA) 230 IgM 230 IgM 20, 2 870% ; IgM ( 2593% ) ( 640% ) ( = 1143, P 005); IgM 3158% ( 6 /19), IgM 853% ( 11/ 129), (P 005) IgM ; ; ; IgM The clinical value of detecting RVIgM antibody in sera of pregnant wom en XIA X iuling. Ch ild H ealth CareH osp ital, L inqing C ity, Shand ong P rov ince 252600, China Abstract Objective T o inve tigate the clin ical value of detecting RV IgM antibody in era of preg nan t wom en. M ethods Enzym elinked mi muno orbent a ay( ELISA) wa u ed to detectRVIgM pecific an tibody in era of pregnant wom enR esults The po itive rate of RVIgM of the 230 pregnant w om en w ere 870% ( 20 /230); The po itive rate ofRVIgM in mu ltigravida ( 2593% ) wa marked ly h igher than prmi igrav 2 id w om en ( 640% ) ( = 1143, P 0 05); The early abortion rate of IgM po itive pregnant w om en w a 2 3158% ( 6 / 19), wherea IgM negative pregnant wom en wa 853% ( 11/ 129) ( = 865, P 005) Con clusion the detection of RVIgM pecific antibody in era of p regnant w om en w ill help to predict pregnancy outcom e, and reduce the frequency of congenital rubella yndrom e infant K ey words Pregnancy; Rubella viru; Enzym elinked mi m uno orbent a ay ( ELISA); IgM 450nm OD , : IgM , OD / OD 10 , 5, 3 IgM ; IgM , , ; IgM 19 , IgM 129 ( congenital rubella yndrom e, CR S ) [ 1] 2 4 IgM , , , P 005 , , 2