塞来昔布胶囊治疗带状疱疹神经痛的有效性.pdf

　　《中国医学创新》第 11 卷 第 4 期（总第 286 期）2014 年 2 月 临床研究 Linchuangyanjiu 塞来昔布胶囊治疗带状疱疹神经痛的有效性 何永超① 【摘要】　目的： 方法： 　　 探讨塞来昔布胶囊治疗带状疱疹神经痛的有效性。 纳入确诊带状疱疹神经痛患者 86 例，阿昔洛韦、维生素 B 等 常规药物治疗基础上，观察组 46 例给服塞来昔布胶囊，对照组 40 例给服布洛芬胶囊。疗程 4 周。结果：观察组、对照组治疗总有效率分别 为 82.6%、62.5%，两组比较差异有统计学意义（P0.05）；治疗后 2 周起两组间 VAS 评分、McGill 得分差异显著，观察组疗效优于对照组， 两组比较差异均有统计学意义（P0.05）。结论：塞来昔布胶囊是治疗带状疱疹患者神经痛的有效药物。 【关键词】　 　　 塞来昔布胶囊；　带状疱疹神经痛；　有效性 　　Preliminary Evaluation on Therapy on the Effectiveness of Herpes Zoster Neuralgia with Celecoxib Capsules/HE Yong-chao.//Medical Innovation of China，2014，11（04）：018-019 　　【Abstract】　Objective： To explore the curative effect of celecoxib capsules on the herpes zoster neuralgia. Method： Eighty-six cases of patients with Herpes zoster neuralgia were divided into two groups， the observation group（n=46） was given celecoxib capsules， and the control group（n=40） was given Ibuprofen. Result： The clinical effective rate of the observation group and the control group were 82.6%， 62.5% respectively， and the difference between the two groups were statistically significant（P0.05）. After the treatment of 2 weeks， the VAS and McGill scores between two groups had significantly difference， the curative effect of the observation group was better than the control group， and the difference between the two groups were statistically significant（P0.05）. Conclusion： Celebrex contributes is an effective drug for the treatment of herpes zoster neuralgia. 　　【Key words】　Celecoxib capsules；　Herpes zoster neuralgia；　Effectiveness ’ 　　First-author s address： Pengpai Memorial Hospital of Haifeng，Haifeng 516400，China 　　doi：10.3969/j.issn.1674-4985.2014.04.008 　　带状疱疹（herpes zoster，HZ）是水痘 - 带状疱疹病毒 1　资料与方法 引起的常见病毒性皮肤病，好发于老年人，主要临床表现 1.1　一般资料　选择本科住院及门诊患者 86 例，入选病例 为沿一侧周