Logistic回归及ROC曲线综合评价超声造影对乳腺癌的诊断价值.pdf

1058 塞旦医堂盘查2鲤生笺箜鲞箜!塑 回归及ROC曲线综合评价超声造影对 Logistic 乳腺癌的诊断价值 沈嫱宋光辉张建兴林勇 党欢 摘要 目的：应用Imgistic回归模型及受试者工作特征曲线(ROC曲线)探讨超声造影综合指标在乳腺癌诊 断中的应用价值。方法：92例乳腺肿块患者术前行超声造影检查，通过Logistic逐步回归分析．对超声造影诊断乳 腺癌的多项指标进行筛选。建立乳腺癌诊断的统计模型即回归方程，并应用ROC曲线评价回归方程的诊断效能 和最佳诊断分界值。结果：超声造影时间一强度曲线上升支斜率和乳腺肿块内血流形态联合诊断乳腺癌的ROC 95．8％、84．2％、91．3％。结论：联合上升支斜率、血流形态的回归方程有助于提高超声造影时乳腺癌的诊断效能，优 于单一指标的检测。 ROE曲线；超声检查； 造影剂 关键词乳腺肿瘤；Logistic模型； valueofcontrast-enhancedforbreast ROC evaluationofthe cancer Comprehensive diagnostic sonography by curveand SHEN logistic Guang-hui，ZHANGJian—xing，LIN regressionQiang，SONG Yong，DANGHuan．Department TraditionalChinese of Hospital，GuangzhouUniversityof Ultrasonography，Second彤l池d 510120，China To the valueofcontrast-enhancedforbreastcancer 【Abstract】Objectiveexplorediagnostic sonography by receiver characteristic amodelof Contrast—enhanced operating curve(ROCcurve)andlogisticregression．Methods in womenwith Was 92 breastmass．After the with sonography analyzingsonographiefindings performedpreoperatively screened forbreastcancerandestablishedamathematical logisticstepwiseregression，wemultiplediagnosticparameters modelfor weassessedthe ofthemodelandcalculatedthe cut·off for diagnosis．Then