武汉市成年人骨密度影响因素分析.pdfVIP

《海南医学》2012 年第23 卷第7 期 HAINAN MEDICAL JOURNAL Vol.23 No.7 April 2012 doi: 10.3969/j.issn. 1003-6350.2012.07.003 ·论 著· 武汉市成年人骨密度影响因素分析 * 蔡玉立，文重远，孙永林，王 颖 （武汉大学人民医院内分泌科，湖北 武汉 430060 ） 【摘要】 目的 探讨武汉市成年人骨密度(Bone mineral density ，BMD) 的影响因素。方法 对379 例18岁 以上体检者应用双能X 线骨密度仪（Dual-energy X-absorptiometry ，DEXA ）测定正位腰椎骨密度值，并进行问卷 调查，对所获资料进行t检验、相关分析及逐步回归分析。结果 男性、女性随年龄变化BMD 变化规律不同，年 龄与BMD 呈负相关(r=-0.244 ，P0.01) ，体重与BMD 呈正相关(r=0.250, P0.01) ，已绝经妇女BMD 低于未绝经 者(P0.01) ，有高血压、冠心病病史者BMD 低于未患病者(P0.01) 。结论 武汉地区成年人BMD 与多种因素有 关，年龄、体重、绝经是重要因素，患有高血压、冠心病者应注意防治骨质疏松。 【关键词】 骨密度；年龄；体重；绝经；影响因素 【中图分类号】 R 194.3 【文献标识码】A 【文章编号】 1003—6350（2012 ）07—006—04 Analysis on the influencing factors of bone mineral density among adults in Wuhan city. CAIYu-li,WEN Zhong-yuan,SUNYong-lin,WANGYing.DepartmentofEndocrinolgy RenminHospitalofWuhanUniversity,Wuhan 430060,Hubei,CHINA 【Abstract 】 Objective To investigate the influencing factors of bone mineral density (BMD) among adults in Wuhan city. Methods Dual-energy X-absorptiometry (DEXA) were used to measure BMD at the lumbar spine among 379 adults. At the same time a questionnaire was conducted among these subjects. The data was analyzed by in- dependent samples t test, bivariate correlation analysis and stepwise regression analysis. Results With the age chang- ing, males and females tend to have different BMD variation. Age and BMD was found to be negatively correlated (r=-0.244, P0.01), while body weight and BMD was found to be positively correlated (r=0.250, P0.01). The BMD from postmenopausal