益气健脾法对AIDS患者免疫重建的理论和临床的研究.pdfVIP

关键词 艾滋病 益气健脾 免疫重建 The theory and clinical research of YiQiJianPi on immunity- reconstruction in AIDS patients Speciality: Dermatology,Surgery of TCM Author: Shi Chuankui Tutor: Professor Du Xixian ABSTRACT 1 Objective Observed in patients before and after treatment of AIDS symptoms, signs, points change, quality of life impact. Indicators of T cell activation in peripheral blood CD4 + T lymphocytes, CD8 + T lymphocytes, CD4/CD8, CD4 + CD45RA, HIV viral load and IL-2, IL-10, TNF and other cytokines at different time points of change. Of the side effects on immune function, for in-depth study of Chinese medicine for HIV / AIDS impact of immune reconstitution to provide clinical basis. 2 Method Strictly meet the test requirements of the AIDS screening 60 patients were already taking HAART drugs, based on randomly divided into two groups of 30 cases. Anti-HIV group were given two sides (AZT +3 TC + NVP) + Chinese and anti-HIV group side (AZT +3 TC + NVP). Two groups of patients were in the treatment of the first 0,3,6, months, signs of change in clinical symptoms, the CD4 + T lymphocytes, CD8 + T lymphocytes, CD4/CD8, CD4 + CD45RA, viral load testing, while the first month safety index 0,6 blood, urine, X ray, electrocardiogram, liver function, kidney function measurement. 3 Results In the combination therapy group and the control group were initial symptom total score of 20.37 ± 3.98 and 22.1 ± 6.04 (P 0.05); three months were 13.30 ± 4.12 and 15.70 ± 5.07 (P 0.05); 6 months was 3.46 ± 2.34, respectively, and 12.10 ± 4.13 (P 0.01), total score of symptoms and signs HAART was better than the control group. Carlo Minkowski integral combination therapy group were in each month aft