Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder》.pdfVIP

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Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder》.pdf

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Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder》.pdf

Biochemical and Biophysical Research Communications 459 (2015) 416e423 Contents lists available at ScienceDirect Biochemical and Biophysical Research Communications journal homepage: /locate/ybbrc Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder a, 1 b, 1 c b d Ya-Di He , Zi-Huan Luo , Ming Yang , Xing-Xing Ruan , Shao-Yuan Liu , Zhen-Quan Wu d, Wei-Ming Deng e, Chun-Kui Shao f, Zu-Lan Su f, Dan He f, Xin Gao b, Liao-Yuan Li b, * a Center of Health Care, The Third Afﬁ liated Hospital, Sun Yat-sen University, Guangzhou, 510630, China b Department of Urology, The Third Afﬁ liated Hospital, Sun Yat-sen University, Guangzhou, 510630, China c Department of Urology, Foshan Hospital of Traditional Medicine, Foshan, 528000, China d Department of Urology, Foshan First Municipal Peoples Hospital, Sun Yat-sen University, Foshan, 528000, China e Department of Urology, The First Afﬁ liated Hospital, University of South China, Hengyang, 421000, China f Department of Pathology, The Third Afﬁ liated Hospital, Sun Yat-sen University, Guangzhou, 510630, China a r t i c l e i n f o a b s t r a c t Article history: Metastasis is the main cause of death from muscle-invasive urothelial carcinoma of the bladder (UCB), Received 19 February 2015 and the metastatic potential of tumors is often unpredictable. The role of Dachshund homolog 2 gene Available online 2 March 2015 (DACH2) in tumo