Prognostic factors in spinal chordoma A systematic review》.pdf

Clinical Neurology and Neurosurgery 139 (2015) 110–118 Contents lists available at ScienceDirect Clinical Neurology and Neurosurgery j o u r n a l h o m ep a g e: w w w. elsev /lo ca t e /cl i neuro Review Prognostic factors in spinal chordoma: A systematic review Ming-Xiang Zou a , Wei Huang b , Xiao-Bin Wang a , Jing Li a,∗ , Guo-Hua Lv a , You-Wen Deng a a Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China b Department of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan 410078, China a r t i c l e i n f o a b s t r a c t Article history: Objective: Discovering reliable prognostic factors for spinal chordoma remains a challenge. We attempted Received 9 February 2015 to identify evidence-based prognostic factors in the literature since its inception and to establish pooled Received in revised form 10 May 2015 relative risks (RR) of such factors. Accepted 20 September 2015 Methods: MEDLINE and Embase search (inception to December 2014). Two reviewers independently selected papers involving spinal chordoma prognostic factors, and studied them for methodological Keywords: quality and valuable new factors. Subsequently, we attempted to pool the results. Chordoma