《3D graphical visualization of the genetic architectures underlying complex traits in multiple environments》.pdfVIP

Hu et al. / J Zhejiang Univ Sci A 2007 8(4):563-567 563 Journal of Zhejiang University SCIENCE A ISSN 1673-565X (Print); ISSN 1862-1775 (Online) /jzus; E-mail: jzus@ 3D graphical visualization of the genetic architectures underlying * complex traits in multiple environments HU Cheng-cheng†1 †‡1 1 2 3 3 , YE Xiu-zi , ZHANG Yin , YU Rong-dong , YANG Jian , ZHU Jun 1 ( College of Computer Science, Zhejiang University, Hangzhou 310027, China) (2James D. Watson Institute of Genomic Science, Zhejiang University, Hangzhou 310029, China) (3Institute of Bioinformatics, Zhejiang University, Hangzhou 310029, China ) †E-mail: cechu@; yxz@ Received Mar. 20, 2006; revision accepted Jul. 23, 2006 Abstract: An approach for generating interactive 3D graphical visualization of the genetic architectures of complex traits in multiple environments is described. 3D graphical visualization is utilized for making improvements on traditional plots in quan- titative trait locus (QTL) mapping analysis. Interactive 3D graphical visualization for abstract expression of QTL, epistasis and their environmental interactions for experimental populations was developed in framework of user-friendly software QTLNetwork (/software/qtlnetwork). Novel definition of graphical m