超声波辐射下离子液体催化合成4-羟基-6-甲基-[1-(苯基亚氨基)乙基]-2H-吡喃-2-酮衍生物有机化学.pdfVIP

DOI: 10.6023/cjoc201204020 研究简报 有机化学 Chinese Journal of Organic Chemistry NOTE 超声波辐射下离子液体催化合成4-羟基-6- 甲基-[1-(苯基亚氨基)乙 基]-2H-吡喃-2-酮衍生物 李大庆 臧洪俊* 吴长春 卢 波 程博闻 (天津工业大学环境与化学工程学院 天津改性与功能纤维重点实验室 天津 300387) 摘要 以离子液体[BMIM-HSO ]HSO 为催化剂, 在超声波辐射下, 脱氢乙酸与芳香胺反应合成了一系列 4-羟基-6- 甲 3 4 基-[1-(苯基亚氨基) 乙基]-2H-吡喃-2-酮衍生物. 实验中考察了催化剂、催化剂用量、反应温度、溶剂对反应的影响, 确 定了最佳反应条件, 给出了可能的反应机理. 该合成方法具有反应时间短、产率高、环境友好、后处理方便、催化剂 可重复使用等优点. 关键词 离子液体; 超声波; 脱氢乙酸; 胺 Synthesis of 4-Hydroxy-6-methyl-[(1-phenylimino)ethyl]-2H-pyran-2- one Derivatives Catalyzed by Ionic Liquid [BMIM-HSO ]HSO under 3 4 Ultrasound Li, Daqing Zang, Hongjun* Wu, Changchun Lu, Bo Cheng, Bowen (State Key Laboratory of Hollow Fiber Membrane Material and Processes, Department of Environmental and Chemistry En- gineering, Tianjin Polytechnic University, Tianjin 300387) Abstract 4-Hydroxy-6-methyl-[(1-phenylimino)ethyl)]-2H-pyran-2-one derivatives have been synthesized via the reaction of dehydroacetic acid and amine in the presence of the ionic liquid [BMIM-HSO ]HSO under ultrasonic irradiation. The ef- 3 4 fect of catalyst, catalyst amount, reaction temperature and solvent on the yield was investigated. The optimum reaction condi- tion was determined and the possible mechanism was proposed. This method has