pH响应胶束3.pdfVIP

Journal of Materials Chemistry B . 9 3 : View Article Online 3 1 : PAPER 4 View Journal | View Issue 1 5 1 0 2 / 8 0 / pH-sensitive short worm-like micelles targeting 2 2 n o tumors based on the extracellular pH† s e Cite this: J. Mater. Chem. B, 2014, 2, c n e 6363 a b c a i c Jung Ok Lee,‡ Kyung Taek Oh,‡ Dongin Kim and Eun Seong Lee* S f o y We developed novel photosensitizing drug-carrying worm-like micelles using a pH-sensitive AB2 miktoarm m e block copolymer consisting of one methoxy-poly(ethylene glycol) (mPEG) block (A) and two d a c 3-diethylaminopropylated poly(L-lysine) [poly(Lys-DEAP)] blocks (B ). In particular, the Y-shaped AB A 2 2 e s miktoarm block copolymer structure mimicking the phospholipid structure enabled the facile e n i preparation of worm-like micelles. The unique feature of pH-responsive DEAP as a hydrophobic moiety h C e