a randomised trial comparing the effect of exercise training and weight loss on microvascular function in coronary artery disease:一项随机试验比较运动训练和减肥对冠状动脉疾病微血管功能的影响.pdfVIP
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a randomised trial comparing the effect of exercise training and weight loss on microvascular function in coronary artery disease:一项随机试验比较运动训练和减肥对冠状动脉疾病微血管功能的影响
International Journal of Cardiology 185 (2015) 229–235
Contents lists available at ScienceDirect
International Journal of Cardiology
journal homepage: www. else vi er. com/ locate/ijcard
A randomised trial comparing the effect of exercise training and weight
,
☆ ☆☆
loss on microvascular function in coronary artery disease
Rasmus Huan Olsen a,⁎, Lene Rørholm Pedersen a, Anders Jürs a, Martin Snoer a,
Steen B. Haugaard b, Eva Prescott a
a Department of Cardiology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark
b Department of Internal Medicine, Amager Hospital Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark
a r t i c l e i n f o a b s t r a c t
Article history: Background: Coronary microvascular function is associated with outcome and is reduced in coronary artery dis-
Received 5 December 2014 ease (CAD) and obesity. We compared the effect of aerobic interval training (AIT) and weight loss on coronary
Accepted 7 March 2015 flow reserve (CFR) and peripheral vascular function in revascularised obese CAD patients.
Available online 11 March 2015 Methods and results: Seventy non-diabetic patients (BMI 28–40 kg×m−2, age 45–75 years) were randomised to
12 weeks AIT (thr
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