住院2型糖尿病者糖尿病高危足筛查分析.pdf

2 住院 型糖尿病患者糖尿病高危足筛查分析 中文摘要 住院2 型糖尿病患者糖尿病高危足筛查分析 中文摘要 目的：调查住院2 型糖尿病患者中糖尿病高危足的患病率及相关影响因素。 方法：对838 名住院2 型糖尿病患者进行高危足病筛查，用振动感觉阈值和踝肱指数 评估神经病变和血管病变。剔除12 名踝肱指数异常升高的患者后，筛选出存在神经 病变和/或血管病变的患者，即糖尿病高危足患者；并将其分为三类：单纯性神经病 变、单纯性血管病变、神经血管混合性病变。用logistic 回归模型评估其可能的影响 因素。 结果：在最终的样本 （n= 826 ）中，糖尿病高危足的患病率是30.6% 。在所有高危足 患者中，单纯性神经病变者（69.6% ）较神经血管混合性病变者 （16.2%）和单纯性 血管病变者（14.2%）更为多见。神经病变和血管病变具有相同的危险因素，包括年 龄、糖尿病病程和收缩压升高。神经病变还与重度吸烟史、超敏C 反应蛋白水平升 高有关；血管病变还与高密度脂蛋白胆固醇水平偏低、甘油三酯水平偏高有关。 结论：住院2 型糖尿病患者中糖尿病高危足患病率高；这可能与年龄增长、糖尿病病 程延长、高血压、吸烟、炎症反应和脂代谢紊乱有关。 关键词：糖尿病高危足，振动感觉阈值，踝肱指数 作 者：邹晟怡 指导教师：施毕旻 I Abstract Identifying at-risk foot among hospitalized patients with type 2 diabetes Identifyingat-riskfootamonghospitalized patientswithtype2diabetes Abstract Aims: To investigate the prevalence and associated factors of diabetic at-risk foot among hospitalized patients with type 2 diabetes. Methods: A total of 838 hospitalized patients with type 2 diabetes were screened for at-risk foot. Neural and vascular disorders were evaluated by assessing vibration perception thresholds and ankle brachial indexes (ABIs). After excluding 12 patients with abnormally high ABIs, remaining individuals with neural and/or vascular disorder were identified as at-risk patients and further classified into three subtypes: isolated neural disorder, isolated vascular disorder and mixed disorder. Potential associated factors were examined using logistic regression models. Results:In the final sample of 826 individuals, the prevalence of diabetic at-ris