托烷司琼复合利卡因预防丙泊酚注射痛的疗效观察.pdfVIP

㈣㈣ l…㈣㈣ 862 Y1892 目 录． 一、摘要 中文论著摘要·····························”一一一一一一一·······1 英文论著摘要······························一一一一一············3 二、英文缩略语··············································-·······5 三、论文 前言····························································6刖百。‘。·。‘。。‘‘‘。‘·‘··。‘‘。。‘。。’’。··。‘。‘‘。‘。。‘。···。。‘。’·。·。。。·。。。。6 材料与方法·····································-················6 实验结果························································9 讨论···························································1l 结论·········-·················································12 四、本研究创新性的自我评价·········································13 五、参考文献·······················································14 六、附录 综述····················································-······16 在校期问科研成绩···············································25 致谢···························································26 个人简介·······················································27 ·中文论著摘要· 托烷司琼复合利多卡因预防丙泊酚注射痛的疗效观察 目的 利多卡因已普遍用于预防丙泊酚注射痛的发生。目前已有关于托烷司琼用于 预防丙泊酚注射痛的研究，但未见托烷司琼复合利多卡因预防丙泊酚注射痛的报 道。本研究在于观察托烷司琼复合利多卡因预防丙泊酚注射痛的疗效。 材料和方法 一、病例 40—80 2％ 卡因40mg。 二、方法 经患者手背桡侧最粗可见静脉给药，给药前关闭输液通道，将袖带血压计加 压至平均动脉压，然后按组别以0．5ml。／s的速度给予不同的药物，60s后松丌袖 带，再以同样速度按1．5—2．Omg／kg静脉注射丙泊酚。再给予0．05mg／kg咪唑安定， 0．6ug／kg的舒芬太尼，0．2mg／kgJll页式阿曲库胺，待患者意识消失，肌松满意后行 气管插管，气管插管后接麻醉机行机械通气，潮气量(VT)8-10mmL／kg，呼吸频率 法观察每组疼痛的发生率及程度。 三、统计分析方法 应用SPSSIO．0软件进行统计分析，计量资料均以均数±标准差表示，组间比 较采用方差分析；计数资料采用卡方检验。以P0．05为有统计学意义。 实验结果 四组患者的性别、年龄、身高、体重、麻醉诱导前基础心率、麻醉诱导前平 均动脉压比较无明显差别，麻醉诱导后平均动脉压较麻醉诱导前均有显著下降， 但组内无显著差。II、Ⅲ、