活血补肾综合疗治疗慢性盆腔炎疗效评价及调控模型大鼠血管内皮细胞功能、抗粘连机制的研究.pdfVIP

MMP-2 的表达优于其他治疗组。 结论：活血补肾综合疗法治疗本病安全有效，值得临床推广使用。通过对慢性盆 腔炎模型大鼠血管内皮细胞因子、抗粘连相关指标的调控，使机体血管扩张，改善循 环状态，增加盆腔有效循环血流量，从而改善了盆腔缺血缺氧的瘀血状况，促进炎症 的吸收以及萎缩腺体的恢复，松解盆腔粘连。 关键词 慢性盆腔炎；活血补肾法；综合疗法；血管内皮细胞功能；抗粘连 1 The Clinic Effect Evaluation of Activating Blood and Tonifying the Kidney on Comprehensive Treating Chronic Pelvic Inflammatory Disease and Experimental Study on The Effects on Endothelial Function and Antiadhesion of the Experimental Model Rats Speciality：Gynecology of TCM Author ：YuYuan-yuan Tutor： Pro.Liu Rui-fen Abstract Objective ：To evaluate the clinic effect of chronic pelvic inflammatory disease (CPID)of blood stagnate and deficiency of the kidney treated by comprehensive treatmen,and providing evidences for clinical scientific application.To explore the mechanism of the treatment of promoting blood circulation and tonifying the kidney comprehensive treatment on the rats with chronic pelvic inflammatory disease （CPID ） by observing the changes of endothelial function and antiadhesion. Methods ：The subject used randomized，multi-center ， blinded evaluation of test method,162 cases of chronic pelvic inflammatory disease of blood stagnate and deficiency of the kidney were divided into two groups randomly; treatment group had 79 cases that is PEN QIANG YAN Recipe+PEN YAN XIAO enema+dreg sextem alapplication therapy; control group had 83 cases that is PEN QIANG YAN Recipe. Observe clinical efficiency, Traditional Chinese medicine symptoms ，physical signs and quality of life after the treatment. Female Wistar rats were used and the CPID model was established with sleeping deprived+ring terrified+mixed bacteria injection+mechanic injury. Seventy-two rats were randomly divided into normal group ，