肺络宁合剂治疗性阻塞性肺疾病急性加重期痰热瘀肺证的临床研究及对血浆NO、ET-1的影响.pdfVIP

Clinical Research with Feiluo ning Mixture on the phlegm heat stasis lung of acute exacerbation of COPD and plasma of NO,ET-1 Speciality: The research of Lung Disease. Medicine of TCM Author:Gao Peng Tutor: Professor Zheng Xin Abstract Objective: To observe the Clinical Research with Feiluo ning Mixture on the phlegm heat stasis lung of acute exacerbation of COPD, as well as on plasma nitric oxide (NO), plasma endothelin -1 (ET-1) level the impact of changes of the Feiluo ning Mixture treatment of acute exacerbation of COPD of the mechanisms and significance, to provide reliable experimental basis for clinical treatment of acute exacerbation of COPD. Methods: ninety patients with acute exacerbation of COPD of phlegm heat stasis of thelung were randomly divided into three groups of 30 people each, 30 cases of the combination therapy group (Chinese and Western medicine + Acupoint Application + antibiotics + bronchodilator + expectorant drugs), 30 cases of Chinese medicine treatment group (medicine + Acupoint Application), Western medicine treatment group (antibiotic + Bronchodilators + expectorantdrugs) 30 cases.Treatment for 14 days. Observed before and after treatment the patients symptoms, signs, blood gas analysis changes, using the ELISA method for the determination of plasma nitric oxide (NO), plasma endothelin -1 (ET-1) expression levels to determine the clinical efficacy. SPSS17.0 software is available for all experimental data statistics . Results:The three groups after treatment, clinical efficiency and the signs and symptoms There were significant differences (P 0.05), Chinese and Western medicine combined treatment group, there are more efficient than the other two groups (P 0.05), and Chinese medicine treatment were