补益肾气法干预年人高血压病肾气亏虚证性激素水平及性激素受体表达的机制研究.pdf

Mechanism Research on Invigorating Kidney Qi Method Intervention the Level of Sex Hormones and Sex Hormone Receptor Expression of Elderly Hypertension Kidney-qi Deficiency Syndrome Specialty: The study of cardiovascular diseases,Internal medicine of TCM Author: Zhang Lei Tutor: Prof.Guo Weixing Abstract This study comes from the tutor Guo Weixing professor of the National Natural Science Fund Project (NO kidney tonifying herbs intervention of elderly hypertension kidney-qi deficiency syndrome sex hormone receptor expression and control mechanism research . Objective: Explore the features of sex hormone and sex hormone receptor expression profiles Which is closely related to the elderly hypertension kidney-qi deficiency syndrome to find the elderly hypertensive kidney-qi deficiency syndrome and sex hormone metabolism and receptor expression in abnormal relationship between. Study of the elderly hypertension patients with deficiency of kidney-qi sex hormone level and its receptor expression intensity changes by the Invigorating kidney qi method before and after intervention, in order to determine the Yi Shen Antihypertension Granule to intervene in the disease of sex hormone, sex hormone receptor level on the targets and mechanisms of action. At the same time to explore the Yi Shen Antihypertension Granule on this type of essential hypertensive patients clinical efficacy, for invigorating kidney qi method in treatment of elderly hypertensive disease and provide a theoretical basis. Method: Collection of the elderly hypertension kidney-qi deficiency syndrome in patients with 60 people cases ( male 30, female 30 ) into the kidney deficiency group, the elderly hypertensive l