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* This is the baseline for recanalization of wide-neck aneurysms…both studies are well-respected benchmarks by the Interventional Neuro Community. * * * * * * * This data shows a strong trend, and we are working to formalize and build on this evidence moving forward, as we feel like continued research will show similar results. * This kind of situation has implications in terms of vessel/aneurysm re-access, as well as safety implications…thrombogenicity. Message - Vessel Conformability is CRITICAL, and can be optimized via an open-cell design, where the cells move independently from one another…this facilitates: Conformability in Tapered Vessels Conformability in Tortuous Anatomy Segment Purchase in Vessel at proximal/mid/distal portion of stent Appropriate Scaffolding at Neck, particularly with Treo Design. Enterprise is going to come hard at us based on pictures they took with the NF2 Stent (2-Interconnect). Their attacks will relate directly to stent herniation into the aneurysm dome. We need to SELL the Treo design improvements hard, to minimize the damage from these imminent attacks. We also need to throw Enterprise under the bus based on association with the other closed-cell intracranial stent (Balt Leo in Europe…high thromboembolic complication rates as reported in Italian MM Conferences). * Stent ovalizes, just like a microcatheter would in a severe bend. Important question for Closed-Cell Enterprise: How do you pack densely at aneurysm inflow/outflow zone if this is occurring? * * * Neuroform在 Myers Madison的数据 66 例宽颈动脉瘤用Neuroform治疗 44 例在6个月时随访 7% 再通率 Neuroform在 BNI / Clev. Clinic 的数据 61 例宽颈动脉瘤用Neuroform治疗 48 例在6个月时随访 23% 再通率 Neuroform在 Rush Presby 的数据 10 例宽颈动脉瘤用Neuroform治疗 (都用 Treo) 10 例在6个月后随访 0% 再通率 Neuroform在 HDE Study 的数据 30 例宽颈动脉瘤 26 在治疗6个月后随访 0% 再通率 Neuroform 治疗宽颈动脉瘤 再通率比较 单用弹簧圈栓塞 N = 408 例动脉瘤随访结果 38% 再通率 Neuroform加弹簧圈 N = 231 动脉瘤随访结果 13% 再通率 开放式网孔(Neuroform)与闭合式网孔支架(LEO)比较血管的顺应性 NeuroformTM LeoTM Stent Body Stent Body Stent E
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