口蹄疫细胞免疫的研究进展.pdfVIP

生物技术通报 BIO TE CHN OLOG Y B ULLETIN 2009 5 1, 2 1 杜进鑫 王永录 1 ( , 730046; 2 , 730070) : 口蹄疫是世界性重大动物疫病之一, 接种疫苗是预防该病的重要策略之一随 对口蹄疫疫苗及其免疫特性 的深入研究和探讨, 许多学者对口蹄疫细胞免疫机制的研究更进了一步, 就参与口蹄疫细胞免疫的各类细胞及细胞免疫与新 疫苗设计的研究进展作一综述 : FMD 细胞免疫 进展 New Research Progress of Cellular ImmuneM echanism of Foodandmouth Disease 1, 2 1 Du Jinxin W ang Yonglu 1 ( K ey La bora tory of A n mi a l Viro log y of A griculture, S ta teK ey La bora tory of Veterinary E tiol ig ica l B io log y, L anzhou Veterin ary R esearch Institute, 2 Ch inese A cad emy of A gricultura l S c iences, L anzh ou 730046 Co lleg e of Ve terina ry M ed ic ine Gansu Ag ricutura l Un iv ersity, L anzhou 730070) Abstrac:t Footandm ou t disease is one of serious an mi al d iseasesVaccination is one of t e sign ificant preventativem easures W it t e study and exploration of vaccines of FMD and t eir mi mune m ec an ism, m any researc ers ave taken furt er step to study t e celiular mi m unem ec anism of FMDT is paper summ arized various types of mi m une cells participating t e cellu lar mi m une of FMD and t e new researc progress of FMD vaccine design involving cellu lar mi mune m ec an ism K ey w ords: FMD C ellular vaccine Progress ( foot and mout d isease FMDV virus, FM DV ) , FMDV RNA , , RNA 8 500 nt, 5UTRORF , , 3UTR, 5UTR 1 300 nt, VPg poly( C) ;