糖网清治疗单纯型糖尿病视网膜病变的临床研析.docVIP

中文摘要 目的：通过对 30 例糖尿病视网膜病变单纯型（nonproliferative diabetic retinopathy,NPDR）患者应用中药汤剂糖网清治疗前后视力、中医证候及眼底情 况的观察，评价糖网清对单纯型糖尿病视网膜病变的疗效，探讨中医药防治糖尿 病视网膜病变的临床应用价值。 方法：将2008年10月至2010年3月明确诊断，符合糖尿病视网膜病变（单纯 期），并符合中医辨证标准的门诊病人60例按1：1随机分成两组。两组患者在严 格控制血糖的基础上，对照组加服复方血栓通胶囊，一日三次，一次三粒，治疗 组加服中药汤剂糖网清，水煎服，每日一剂，温服，每日早晚各服一次。两组病 例均治疗三个月通过对视力、中医证候、眼底改变等疗效指标的观察对比两种药 物的疗效。 结果：治疗组与对照组在年龄、治疗前血糖、血脂，治疗前视力、治疗前中 医症候积分等方面，经统计学处理，均无明显差异(P＞0.05)具有可比性。治疗 后治疗组对照组视力均有改善(P＞0.05)，两组间无明显差，证明两种药物均可 改善视力；中医证候改善治疗组明显优于对照组(P0.05)，两组间差异有统计学 意义；两组间眼底专科检查疗效比较结果显示:治疗组总有效率90.48%，对照组 总有效率75.56%，经统计学处理P＜0.05，说明治疗组眼底改善情况优于对照组； OPs检查显示治疗组振幅值上升大于对照组，经统计学处理P＜0.05，说明治疗组 视网膜微循环改善情况优于对照组。 结论：糖网清对于单纯型糖尿病视网膜病变疗效显著能有效改善患者全身及 眼底情况，并能提高患者视力。 关键词：糖网清 ；单纯型糖尿病视网膜病变；复方血栓通胶囊；临床研究 Clinical Study On Effects Of Tang Wang Qing In Treatement Of NPDR Abstract Purpose: This dissertation evaluates the curative effects of Tang Wang Qing on nonproliferative diabetic retinopathy (NPDR) based on observation of 30 NPDR patients in terms of sight recovery, TCM syndromes and fundus oculi after they used the traditional Chinese herbal medicine Tang Wang Qing, in quest of the clinical application value of traditional Chinese medicine in curing NPDR. Methodology: 60 patients diagnosed with NPDR from October 2008 to March 2010 in conformity with TCM diagnosis standards were randomly organized into two groups. In strict control of blood sugar, the control group took Fufang Xueshuangtong Jiaonang three times a day, with three capsule each time; the therapy group took about 200ml of warm boiled Tang Wang Qing twice a day in the morning and evening. During tow-month treatment, the curative effects of two different medicines were compared through obeservation on the two groups in terms of sight, TCM syndromes and fundus oculi. Results: The two groups differ little in terms of age, blood sugar lipids, sight, and TCM syndromes before their treatment (P＞0.05). After the treatment, the two groups both have improvements in eye sight (P ＞0.05) with little difference whic