采用低剂量螺旋CT进行肺癌筛查的临床应用价值.docVIP

采用低剂量螺旋CT进行肺癌筛查的临床应用价值 　　[摘要] 目的 探讨一般人群中采用低剂量螺旋CT进行肺癌筛查的临床应用价值。 方法 收集2014年1～12月进行肺部低剂量螺旋CT筛查健康的1122例在职及离退休职工体检结果，年龄18～82岁，平均48岁；男547例，女575例。应用西门子公司Somatom Definition 64排128层CT扫描机，30 mAs，120 kV，低剂量肺部扫描。判断标准：实性或部分实性无钙化结节直径≥5 mm、磨玻璃结节≥8 mm为阳性结节。 结果 1122例健康体检者中，9例（0.8%）被诊断为肺癌。通过低剂量螺旋CT筛查，发现阳性结节者15例（1.3%），阳性结节18个，其中实性结节4个（22.2%），磨玻璃结节14个（77.8%），阳性结节者年龄均在40岁以上，其中50～80岁人群占60%。手术切除10个阳性结节，其中3个（30%）实性结节，7个（70%）磨玻璃结节。 结论 低剂量螺旋CT用于肺癌筛查具有较好的临床应用价值，建议参与体检筛查的人群年龄在40岁及以上。 中国论文网 /6/view-7217641.htm 　　[关键词] 低剂量螺旋CT；肺癌；阳性结节；筛查；健康体检 　　[中图分类号] R734.2 [文献标识码] B [文章编号] 1673-9701（2015）25-0096-03 　　The clinical value of low dose spiral CT in lung carcinoma screening 　　YUAN Ye 　　Department of Radiology， China Aerospace Science Industry Corporation 731 hospital， Beijing 100074， China 　　[Abstract] Objective To evaluate the clinical value of low dose spiral CT in lung carcinoma screening. Methods A total of 1 122 staffs and retirees who took the physical examination in the hospital from Jan to Dec 2014 were investigated. All participates were checked-up by low dose spiral CT examination of the chest. The range of the age was from 18 to 82 years old. The average age was 48. Male 547 cases， and female 575 cases. The Siemens Somatom Definition 64-row 128-slice was applied， and the scan parameters were 30 mAs， and 120 kV. When the diameter of solid nodule or part of solid calcified nodule was more than 5 mm， it was considered to be positive nodules. Also， when the diameter of ground glass nodules was more than 8 mm， it was considered to be positive nodules. Results Among the 1 122 physical examination participants， 9 cases（0.8%） were diagnosed as lung carcinoma. By low dose spiral CT screening， 15 cases（1.3%） who had positive nodules were found. There were 18 positive nodules in total， including 4（22.2%） solid nodules and 14 （77.8%） ground glass nodules. The age of patients who had positive nodules was over 40 years old， and the proportion of the patients of 50-80 years old accounted for 60