降糖药联合桑白皮总黄酮治疗糖尿病的疗效观察重点分析.docVIP

降糖药联合桑白皮总黄酮治疗糖尿病的疗效观察 吴国龙(广东省深圳市宝安区人民医院兴东社区健康服务中心　518101) 郑定容(广东省深圳市宝安区中心医院社区健康服务管理中心，518102) [摘要]目的 比较采用降糖药联合桑白皮总黄酮与单纯采用降糖药治疗Ⅱ型糖尿病(T2DM)的疗效。 方法 将随机选取200例T2DM病患者分为治疗组和对照组各100例，对照组采用西医常规治疗，治疗组在对照组治疗基础上加用合桑白皮活性成分提纯物治疗，治疗3个月后，统计临床疗效，并观察治疗前后血糖变化情况。 结果 治疗后，治疗组总有效率95%优于对照组总有效率73%，比较差异有统计学意义(P0.05)；治疗组血糖达标时间((Gluct)短于对照组(P0.05)，空腹血糖(FPGlu)、餐后2h血糖(2hPGlu) 、空糖化血红蛋白（HbA1c）、空腹胰岛素（FIns）和空腹C-肽(FCP)水平较本组治疗前均明显降低(P0.05)，且治疗组降低明显优于对照组(P0.05)。 结论 降糖药联合桑白皮总黄酮治疗T2DM能减少胰岛素过度分泌，可以保护胰岛β细胞功能，有效控制T2DM病患者的血糖，达到治疗糖尿病的目的。 [关键词] 糖尿病；降糖药；中药；桑白皮；胰岛素；血糖 Efficacy of hypoglycemic agents combined total flavonoids from the root bark of Morus alba to treat diabetes Wu Guolong(Guangdong province Shenzhen Baoan District Peoples hospital 518101) Zhengding Rong (Guangdong Province, Shenzhen Baoan District Central Hospital Community Health Services Management Centre, 518102) [Abstract] Objective Comparison of efficacy Ⅱ diabetes mellitus (T2DM) used hypoglycemic agents combined total flavonoids from the root bark of Morus alba and the simple use of hypoglycemic therapy. Methods The randomly selected 200 cases of T2DM patients were divided into treatment group and control group (100), The control group used conventional Western medicine,The treatment group were treated based on the active ingredients used together Morus alba purification therapy, after three months of treatment, the clinical efficacy of statistics and observe changes in blood sugar before and after treatment. Results After treatment, the total efficiency in 95% of the treatment group was better than the total efficiency in 73% of the control group; Treated blood glucose time ((Gluct) of the treatment group was shorter than the control group (P 0.05), Fasting plasma glucose (FPGlu), 2h postprandial glucose (2hPGlu), empty glycated hemoglobin (HbA1c), fasting insulin (FIns) and fasting plasma C- peptide (FCP) levels than the group before treatment were significantly lower (P0.05), And the treatment group were significantly lower than