治疗药物监测资料.ppt

治疗药物监测 目 录 理论与方法 流程与要点 回顾与展望 治疗药物监测－理论与方法 定义 治疗药物监测（Therapeutic Drug Mornitoring，TDM）又称临床药动学监测（clinical pharmacokinetic monitoring, CPM），是指根据药动学原理，采用现代分析手段，对血液和其他体液中的药物浓度进行测定并取得有关参数，为临床用药科学化、个体化、合理化提供依据，从而提高药物疗效，避免药物中毒反应。 ——《实验诊断学》 Definitions of  Therapeutic Drug Monitoring  -IATDMCT Proposed by Standards of Laboratory Practice Committee, 2003 Approved by Executive Committee, 2004 Amended by IATDMCT Executive Committee, 2011 Therapeutic drug monitoring is defined as “ the measurement made in the laboratory of a parameter that, with appropri