美皮护用于剖腹产术后瘢痕防治的疗效观察.docVIP

美皮护用于剖腹产术后瘢痕防治的临床疗效观察 张玉秋1 纪向虹1 张淑萍1 1青岛市市立医院 摘要 目的：观察验证美皮护（软聚硅酮敷料）用于预防及治疗剖腹产术后切口部位瘢痕增生的有效性和安全性。 方法：本次研究收集剖腹产术后切口正常愈合患者共28例，其中伤口愈合即使用美皮护的患者25例，发现增生后使用美皮护治疗病例1例，未使用美皮护2例，以VSS评分作为疗效评价指标，以观察治疗效果，并进行统计分析，用 SPSS13.0软件进行数据处理。 结果：美皮护治疗组各阶段VSS量表评分经重复测量方差分析F=18.808，p=0.023。说明剖腹产术后使用美皮护防治瘢痕，瘢痕仍然会逐渐增生，在6个月达高峰，随后逐渐好转。术后9个月美皮护治疗组与对照组VSS量表评分差异有统计学意义（t=3.301，p=0.030），说明美皮护防治瘢痕是有效的。 结论：美皮护用于剖腹产术后瘢痕防治有较好的效果，且创面愈合后开始使用的时间越早，持续贴用时间越长，效果越好；反之，则越差。未使用任何瘢痕防治措施的患者，瘢痕增生有发展更严重的趋势。美皮护是防治剖腹产术后瘢痕增生的一种有效方法。 关键词：瘢痕 美皮护 疗效 软聚硅酮 Abstract Purpose: To observe and test the efficacy and safety of soft silicone dressing (Mepiform) in preventing and treating hypertrophic scars after hysterotokotomy. Method: We collect 28 patients who are incision healed normally after hysterotokotomy in this study. Mepiform was primarily applied to healed incision on 25 patients, applied after hyperplasia on 1 patient, was not applied on 2 patients. We take Vancouver Scar Scale as assessment criteria to observe the clinical efficacy and conduct statistical analysis by?software SPSS13.0. Result: After repeated measures analysis of variance of VSS score of Mepiform group in different stage, we find that F=18.808 and p=0.023. The result prove that the scars will continue hyperplasia even if Mepiform was used to treat scares after hyperplasia, and the hyperplasia reached the peak 6 months later, after that it took a turn for the better gradually. 9 months after surgery, the difference of VSS score between the treatment group of Mepiform and controlled group has statistical significance which proved that Mepiform is effective in prevent and treat scars. Conclusion: Mepiform attains better result in preventing and treating the scares after hysterotokotomy. When it is used earlier and longer after wound healing, the effect is better. Conversely, the effect is worse. For patients who do not use any scars preventions, their hypertrophic scars have trend of more serious. Mepiform is used as an effective way to prevent and tre