降血脂药物在急性冠心症及脑中风的使用课件.ppt

Use of Lipid-lowering Agent in Acute Coronary Syndrome and Ischemic Stroke in Taiwan Yi-Heng Li, MD, PhD Department of Internal Medicine College of Medicine National Cheng Kung University Liao JK. Am J Cardiol. 2005;96(suppl 1):24F-33F. MMPs = matrix metalloproteinases ? Platelet activation ? Coagulation ? Endothelial  progenitor cells ? Effects on collagen ? MMPs ? AT1 receptor ? VSMC proliferation ? Endothelin ? Macrophages ? Inflammation ? Immunomodulation ? Endothelial function ? Reactive oxygen  species ? NO bioactivity Pleiotropic effects of statins Statins Statin in Acute Co