MS-introduction.pptVIP

Fast Atom Bombardment (FAB) The sample is dissolved in a liquid matrix such as glycerol, thioglycerol, m-nitrobenzyl alcohol, or diethanolamine and a small amount (about 1 microliter) is placed on a target. The target is bombarded with a fast atom beam (for example, 6 keV xenon atoms) that desorb molecular-like ions and fragments from the analyte. Cluster ions from the liquid matrix are also desorbed and produce a chemical background that varies with the matrix used. Xe e- Xe+? + Xe Xe+? Is accelerated to ~6-10 keV, and pass through Xe Xe + Xe+? Xe (Xenon with Kinetic energy) FAB FAB: Bene