恶性骨肿瘤的证候调查和益气活血化痰法干预荷瘤小鼠的实验研究.pdf

优于中、低剂量组 P O．05 ． 结论：加味四物汤高剂量组可以抑制荷瘤小鼠体内肿瘤的生长，通过抑制 ，岖GF、KDR，Flt一1的表达控制肿瘤新生血管的生长而达到阻止恶性骨肿瘤体内 生长的目的． 关键词中医证候；病因病机：骨肿瘤；临床研究；实验研究 The onthe ofTCM ofmaI i bone study changessyndromesgnant tumor andthe ricaI onherbsof patients empi study VitaI and bIoodfIOWand invigoratingenergypromoting eI mice tumor—bearing iminatingphIegmtreating Abstract SpeciaIity：OrthopaedicsandTraumaofTCM Author：He Renrong Tutor：prof．LiuJinwen Thetotalincidencerateof bonetumoris itoften malignant low，but to the few resultsin andeventhreatlife．Forpast extremitydisability survivalrate raisedsincecombined years，five consumedly therapy year and chemotherapyetc，was includingoperationneoadjuvant applied．TCM， asa ofcombined characteristic part therapy，manifests therapeutic effectand on thefocusof potentialitystabilizing side livetimeand the chemoradiotherapy’Seffect，prolongingimproving oflife．Onaccountofvariouskindsof researchon quality reasons，the TCMis onthe bonetumor malignant by relativelylagging，theknowledge ofthe ofitsTCM andits regularpattern development syndromes still curativeeffectandmechanismof is insufficient，the pathogenesis TCMdemandsbeauthenticatedfurther these to empirical by study．On a on bone madeclinical grounds，thisstudy retrospectivestudymalignant tumor to itsTraditionalChinese patientsexplore Medicine TCM ofitsTCM made andthecharacteristics syndromes pathogenesis，and of onthemechanismofactionthatthemethod experimentalstudy and bloodflowand vital eliminatingphlegm invigoratingenergypromoting totreat bonetumor． malignant PartI The onthe ofTCM study changes syndromes ofmal bonetumorients ignant pat the Aim：This triestofindoutthe ofTCM and study changessyndromes characteristicsofTCM of bonetumor pathogenesismalignant patients， and to fundamentalresearchforclinical and hopesprovide applications scientlficresearch． Method：statisticaloncorrelatedfactors of analysis includingtype TcM of clinical syndromesMM， age， gender， concentration．Bence etc．wascarr