启肝毓坤汤治疗卵巢早衰的效果.docVIP

启肝毓坤汤治疗卵巢早衰的效果 　　[摘要] 目的 探讨启肝毓坤汤治疗卵巢早衰患者的临床效果。 方法 选择2011年3月～2013年12月商丘医学高等专科学校附属医院卵巢早衰患者85例，按就诊顺序分为两组，单号为对照组（39例），双号为治疗组（46例）。对照组采用西药雌孕激素序贯疗法，治疗组采用启肝毓坤汤，两组均连续治疗3个月。比较两组治疗前后临床症状和雌二醇（E2）、促卵泡激素（FSH）、黄体生成激素（LH）的差异。 结果 治疗组总有效率为89.13%，对照组为79.49%，两组比较差异有统计学意义（P 0.05）。治疗后，治疗组心烦急躁、腰酸坠胀消失率（89.47%、87.50%）均高于对照组（77.27%、73.68%），差异均有统计学意义（P 0.05）。治疗前后治疗组E2[（15.39±6.23）、（90.47±7.02）ng/L]、FSH[（81.65±18.12）、（31.25±4.12）U/L]、LH[（42.18±5.52）、（23.46±4.09）U/L]水平比较，差异均有统计学意义（P 0.05）；治疗前后对照组E2[（14.28±5.89）、（57.62±4.75）ng/L]、FSH[（79.24±16.72）、（35.47±5.19）U/L]、LH[（4.13±4.69）、（22.25±4.13）U/L]水平比较，差异均有统计学意义（P 0.05）。治疗后两组E2水平比较，差异有统计学意义（P 0.05）。 结论 启肝毓坤汤可有效改善由卵巢早衰引起的激素水平变化，且能缓解其临床症状，临床疗效较好。 　　[关键词] 启肝毓坤汤；卵巢早衰；促性腺激素 　　[中图分类号] R711.75 [文献标识码] A [文章编号] 1673-7210（2016）03（a）-0108-04 　　Effect of Qiganyukun Decoction in the treatment of patients with premature ovarian failure 　　WANG Xueli WANG Huahang JIANG Bo HU Junming YAN Junying 　　Department of Traditional Chinese Medicine， the Affiliated Hospital of Shangqiu Medical College， Henan Province， Shangqiu 476005， China 　　[Abstract] Objective To investigate the clinical effect of Qiganyukun Decoction in the treatment of patients with premature ovarian failure. Methods 85 patients with premature ovarian failure in the Affiliated Hospital of Shangqiu Medical College from March 2011 to December 2013 were selected， who were divided into two groups according to visiting sequence， 46 cases in treatment group and 39 cases in the control group. Patients in the control group were treated by western medicine sequential therapy of estrogen and progesterone， the treatment group was treated with Qiganyukun Decoction， two groups were continuous treated for 3 months. The differences of clinical symptoms and the levels of hormones before and after treatment were compared. Results The total effective rate of the treatment group was 89.13%， the control group was 79.49%， the difference was statistically significant （P 　　[Key words] Qiganyukun Decoction；