神经外科术后颅内感染的临床研究.docVIP

神经外科术后颅内感染的临床研究 　　【摘要】 目的：分析神经外科术后颅内感染的危险因素，探讨有效的防治措施。方法：选取笔者所在医院收治的36例神经外科术后颅内感染患者的临床资料进行回顾性分析，总结可能存在的危险因素，将其分成对照组与观察组，各18例，对照组单纯应用抗生素治疗，观察组应用鞘内注射万古霉素治疗，对比两组的临床效果。结果：手术时间、术后留置引流管、手术类型、合并基础疾病均是神经外科术后颅内感染的危险因素。观察组总有效率为94.4%，对照组为61.1%，两组比较差异有统计学意义（P0.05）。结论：神经外科术后颅内感染的危险因素很多，应用鞘内注射万古霉素进行治疗的效果显著，值得推广与应用。 　　【关键词】 神经外科手术； 颅内感染； 临床特征； 治疗效果 　　中图分类号 R651.1 文献标识码 A 文章编号 1674-6805（2016）10-0011-02 　　【Abstract】 Objective：To analyze the risk factors of postoperative intracranial infection in department of neurosurgery，and explore the effective prevention measures.Method：The clinical data of 36 intracranial infection patients were selected from our hospital，which were retrospectively analyzed and the possible risk factors were summarized.They were divided into the control group and the observation group，18 cases in each group.The control group was treated with antibiotics alone，the observation group was injected with Vancomycin within the sheath，compared the clinical effects of the two groups.Result：The operation time，postoperative indwelling drainage tube，surgical type，combined with basic diseases were the risks of intracranial infection after operation，the total effective rate of the observation group was 94.4%，the control group was 61.1%，the difference was statistically significant（P0.05）.Conclusion：There are many risk factors of postoperative intracranial infection in department of neurosurgery，and the effect of intrathecal injection of vancomycin is significant，it is worth popularizing and applying. 　　【Key words】 Department of neurosurgery operation； Intracranial infection； Clinical characteristics； Treatment effect 　　First-author’s address：Xiangya Medical College of Central South University Affiliated Tumor Hospital，Changsha 410000，China 　　doi：10.14033/j.cnki.cfmr.2016.10.005 　　在神经外科的临床救治中，由于大部分患者具有发病快、变化快、病情重、死亡率高等特点，使得神经外科成为一个风险系数较高的科室[1-2]。相应的神经外科手术的风险性也较大，发生颅内感染等并发症并不罕见。因此，分析神经外科术后颅内感染的危险因素，进而提出有效的防治措施就显得非常重要。基于此，本文就笔者所在医院神经外科2010年3月-2015年3月接收并治疗的36例患者的临床资料进