多囊卵巢综合征内分泌紊乱患者胰岛素增敏剂治疗效果探讨.docVIP

多囊卵巢综合征内分泌紊乱患者胰岛素增敏剂治疗效果探讨 　　【摘要】 目的：探讨多囊卵巢综合征内分泌紊乱患者胰岛素增敏剂的使用疗效。方法：选择本院2012年8月-2013年11月收治的56例多囊卵巢综合征患者为研究对象，随机数字表法分为对照组28例，观察组28例，对照组行枸橼氯米芬、妈富隆、戊酸雌二醇片联合治疗，观察组在对照组治疗基础上加入胰岛素增敏剂治疗，对两组患者治疗后效果进行分析。结果：观察组治疗总有效率为92.86%，对照组为71.43%，比较差异有统计学意义（P0.05）；观察组患者在各个时间段的胰岛素水平以及胰岛素抵抗指数都明显低于对照组，比较差异有统计学意义（P0.05）。结论：在常规治疗方案基础上加用胰岛素增敏剂对多囊卵巢综合征内分泌紊乱患者进行治疗，效果显著，安全性高，值得临床进一步推广使用。 　　【关键词】 多囊卵巢综合征； 内分泌紊乱； 胰岛素增敏剂 　　Syndrome of Insulin in Patients with Endocrine Disorders Explore Treatment Effect of Sensitizer Polycystic Ovarian Disease/LIANG Chun-yan，TAN Shu-ying，ZHANG Xiao-lu.//Medical Innovation of China，2015，12（16）：054-056 　　【Abstract】 Objective：To investigate the curative effect of polycystic ovary syndrome patients with comprehensive use of insulin sensitizing agent endocrine disorders.Method：In our hospital in 2012 August to 2013 November 56 polycystic ovary syndrome patients were selected as the research objects，and randomly divided into 28 cases in control group and 28 cases in observation group，the control group accpeted citric clomiphene citrate，Marvelon，Xu acid Estradiol Tablets combined treatment，the observation group based on the control group accepted insulin sensitizing sensitive agent treatment，the two groups were analyzed after treatment.Result：In the observation group the total effective rate was 92.86%，71.43% in the control group，the difference was statistically significant （P0.05）.In all the time，insulin levels of the observation group were lower than those of the control group （P0.05）.Conclusion：Based on conventional treatment scheme on the use of insulin sensitizing agent for the treatment of polycystic ovary syndrome，endocrine disorders in patients with significant effect，high safety，is worth to be popularized in clinical use. 　　【Key words】 Polycystic ovary syndrome； Endocrine disorders； Insulin sensitizing agent 　　First-author’s address：The Second People’s Hospital of Foshan City，Foshan 528000，China 　　doi：10.3969/j.issn.1674-4985.2015.16.020 　　多囊卵巢综合征（PCOS