子宫根治性切除手术和放疗治疗早期宫颈癌的临床效果对比.docVIP

子宫根治性切除手术和放疗治疗早期宫颈癌的临床效果对比 　　[摘要] 目的 探讨子宫根治性切除手术和放疗治疗早期宫颈癌的临床效果。 方法 选取早期宫颈癌患者166例，随机将其分为两组，各83例。A组采取子宫根治性切除手术；B组采取放疗。统计两组患者并发症的发生率；于治疗后1年采用宫颈癌患者生活质量量表评价两组患者的生活质量。 结果 A组患者便秘、排尿困难、尿失禁、阴道干燥、性交困难以及潮红发生率分别为71.08%、40.96%、42.17%、36.14%、19.28%和31.33%，明显高于B组（24.10%、14.46%、25.30%、20.48%、8.43%、6.02%）；B组腹痛、腹泻、血便发生率分别为24.10%、44.58%、25.30%，明显高于A组（6.02%、7.23%、2.41%）。两组患者不同并发症的发生率比较差异均有统计学意义（P0.05）。 结论 对早期宫颈癌患者进行治疗时，临床医生可以根据患者的年龄和期望制订个体化的方案，对于有生育需求的中青年患者更倾向于选择放疗；而对于已经没有生育要求的患者，通过手术治疗较好。 　　[关键词] 早期宫颈癌；子宫根治性切除；放疗 　　[中图分类号] R713.4 [文献标识码] A [文章编号] 1674-4721（2015）07（b）-0044-03 　　[Abstract] Objective To explore the clinical effects of radical hysterectomy and radiotherapy in the treatment of early cervical cancer. Methods 166 patients with early cervical cancer were selected，and they were randomly assigned into two groups of 83 patients，making them comparable.Group A was given radical hysterectomy；the group B was given radiotherapy.Incidence of complications in the two groups of patients were statistically collected；one year after the treatment，scale of life quality for patients with cervical cancer was applied to assess the life quality in the two groups of patients. Results Incidences of constipation，dysuria，urinary incontinence，colpoxerosis，dyspareunia and redness were 71.08%，40.96%，42.17%，36.14%，19.28% and 31.33% respectively，which were significantly higher than those in group B （24.10%，14.46%，25.30%，20.48%，8.43%，6.02%）；incidences of abdominal pain，diarrhea and bloody stool were 24.10%，44.58% and 25.30% respectively，which were significantly higher than those in group A（6.02%，7.23%，2.41%）.There were significant differences between incidence of different complications in the two groups of patients （P0.05）. Conclusion In the treatment for patients with early cervical cancer，clinical physicians can formulate individualized protocol according to patients age and expectations.Young and middle-aged patients who are in need of childbearing prefer to radiotherapy；for those who are no