疱疹性口炎应用干扰素雾化及开喉剑的临床观察.docVIP

疱疹性口炎应用干扰素雾化及开喉剑的临床观察 　　摘要： 目的：探讨干扰素雾化及开喉剑联合治疗疱疹性口炎患儿的临床疗效。方法：本研究于2014年1月～2014年12月将收治的64例疱疹性口炎患儿按照数字表法随机分为研究组和对照组，其中对照组在对症支持治疗的基础上仅采用干扰素高频雾化治疗，而研究组则在对症支持治疗的基础上采用干扰素高频雾化联合开喉剑喷雾剂（儿童型）治疗，比较两组患儿的临床治疗效果。结果：经过积极治疗后，研究组中显效16例，占50.00%，有效11例，占34.38%，总有效率达84.38%；对照组中显效10例，占31.25%，有效9例，占28.13%，总有效率为59.38%；经统计分析发现研究组的总有效率明显高于对照组，差异具有统计学意义（x2=4.95，P0.05）。研究组的临床治愈时间[（3.52±1.25）d]较对照组[（6.90±2.64）d]明显缩短，差异具有统计学意义（t=3.98，P0.05）。结论：干扰素高频雾化联合开喉剑治疗疱疹性口炎临床疗效确切，可以有效缩短治愈时间，值得临床推广使用。 　　关键词： 疱疹性口炎；干扰素；雾化；开喉剑 　　Abstract： Objective： To investigate the clinical effect of interferon atomization and Kaihoujian combined treatment of children with herpetic stomatitis. Methods： 64 cases of herpetic stomatitis in accordance with digital table method were randomly divided into study group and control group， the control group in the symptomatic support treatment based on only the interferon high-frequency atomization treatment， while the study group in the symptomatic support treatment based on the high-frequency interferon atomization combined with Kaihoujian （child） treatment， compared two groups of children with clinical therapeutic effect. Results：In the study group， 16 cases were markedly effective， 50.00%， 11 cases were effective， 34.38%， the total effective rate was 84.38%； in the control group， 10 cases were markedly improved， 31.25%， 9 cases were effective， 28.13%， the total efficiency of 59.38%. The total effective rate of study group was significantly higher than that of the control group （x2=4.95， P 0.05）. The clinical cure time of study group [（3.52±1.25）d] was significantly shorter than that in control group [（6.90±2.64）d] （t=3.98， P0.05）. Conclusion： High-frequency interferon atomization and Kaihoujian had good clinical curative effect in treatment of Herpetic stomatitis， and can effectively shorten the healing time. 　　Keywords： Herpetic stomatitis； Interferon； Atomization； Kaihoujian 　　本研究于2014年1月～2014年12月将收治的64例疱疹性口炎患儿按照数字表法随机分为研究组和对照组，其中对照组在对症支持治疗的基础上仅采用干扰素高频雾化治疗，而研究组则在对症支持