缺血性脑卒中老年卒中后抑郁及其与痴呆的关系分析.docVIP

缺血性脑卒中老年卒中后抑郁及其与痴呆的关系分析 　　[摘要] 目的 对老年缺血性脑卒中患者卒中后抑郁（PSD）的发病特点、相关因素及其与痴呆的相关性进行探讨。方法 整群选取该院2013年1月―2014年10月收治的老年缺血性卒中患者156例作为观察组，对老年卒中患者与同期门诊体检健康者作为对照组进行流行病学调查，分别对患者进行简易智能状态检查量表（MMSE）及汉密尔顿抑郁量表（HAMD）对患者抑郁状况和认知状态及情感状态，并进行对比分析。结果 与健康人群（80例）比较，156例脑卒中患者患轻、中、重度PSD的人数明显高于对照组（P0.05）；脑卒中患者中PSD患者并发痴呆发病率显著高于非PSD患者。结论 脑卒中是PSD的发病率的因素，PSD患者更可能并发痴呆。 　　[关键词] 缺血性卒中；老年患者；痴呆；抑郁 　　[中图分类号] R743.3 [文献标识码] A [文章编号] 1674-0742（2015）05（a）-0006-02 　　Analysis of the Post-stroke Depression in the Elderly after Ischemic Stroke and Its Relationship with Dementia 　　HE Ming-wu 　　Department of Neurology， Mianchi County Peoples Hospital， Mianchi， Henan Province， 472400 China 　　[Abstract] Objective To investigate the clinical characteristics and relevant factors of post-stroke depression（PSD） in the elderly after ischemic stroke and its correlation with dementia. Methods 156 elderly patients with ischemic stroke admitted in our hospital from January 2013 to October 2014 were selected as the observation group， and the people underwent physical examination in the clinic during the same period were selected as the control group. Epidemiological survey was conducted in the both groups. The depression and cognitive state and emotional status of the two groups investigated by Mini-Mental State Examination（MMSE） and Hamilton Depression Scale （HAMD） were compared and analyzed. Results Compared with the 80 healthy people in the control group， the number with mild， moderate and severe PSD in the 156 patients with ischemic stroke in the observation group was much more， respectively （P0.05）； and among the patients with ischemic stroke， those cases with PSD had obviously higher incidence of dementia than those without PSD. Conclusion Stroke is a factor causing PSD， and PSD patients are more likely to have dementia. 　　[Key words] Ischemic stroke； Elderly patients； Dementia； Depression 　　抑郁症是老年常见的一种精神疾病，发病率较高，老年抑郁症的发病率约为16%～26%[1]，抑郁症患者占老年人口7%～10%，而对于合并有其他躯体疾病的老年人， 其抑郁发生率可高达50%。 患有中风、心脏病、癌症等疾病的老年人群发生抑郁的风险