急性心肌梗死患者入院24 h内平均血糖水平对临床预后影响.docVIP

急性心肌梗死患者入院24 h内平均血糖水平对临床预后影响 　　[摘要] 目的 探讨ST段抬高心肌梗死患者入院后24 h内平均血糖水平对患者预后的预测价值。 方法 选取2009年1月～2013年2月期间我院收治的STEMI患者195例，按照入院后24 h内MBG水平分为三组，分别为A组（7.8 mmol/L）、B组[（7.8～10.9）mmol/L]、C组（≥11 mmol/L）。记录患者的基线资料、7 d及30 d时主要不良心血管事件的发生情况，比较不同血糖组别之间的不良心血管事件的发生率。 结果 三组在7 d、30 d时心血管事件发生率存在显著性差异（P0.01）；B组和C组在7 d与30 d时心血管事件发生率存在显著性差异（P0.05）。发生率与血糖水平呈正相关。 结论 STEMI患者入院后24 hMBG与近期病死率以及不良心血管事件的发生密切相关。 　　[关键词] STEMI；24 h平均血糖；预后 　　[中图分类号] R542.22 [文献标识码] B [文章编号] 1673-9701（2015）01-0019-03 　　Expression of 24 hour average blood glucose for clinical and prognosis value in patients with ST segment elevation myocardial infarction after admission 　　FU Benxing 　　Department of Internal Medicine，CITIC Central Hospital，Luoyang 471003，China 　　[Abstract] Objective To investigate prediction value and significance level on the prognosis of the patients with the STEMI （ST segment elevation myocardial infarction） MBG 24h in patients after admission （24 hour average blood glucose）. Methods From January 2009 to February 2013， selected 195 cases with ST elevation myocardial infarction， according to the MBG level after 24h in hospital were divided into three groups，group A（7.8 mmol/L），group B [（7.8-10.9） mmol/L]， group C（≥11 mmol/L）. Baseline data at the 7th days and 30th day of major adverse cardiovascular events were recorded， and the incidence of adverse cardiovascular events between different blood groups were compared. Results The cardiovascular events among A group， group B，group C at the 7th days and 30th day showed significant difference（P0.01）； Cardiovascular events of B and C groups at the 7th days and 30th day showed significant difference（P0.05）. Blood glucose level showed positive correlation with cardiovascular events（P0.05）. Conclusion 24h MBG in STEMI patients is closely related to the mortality and adverse cardiovascular events. 　　[Key words] STEMI；24h average blood glucose；Prognosis 　　既往有研究报道，急性心肌梗死患者入院时血糖升高水平与病死率之间密切相关[1]。由于入院时血糖具有波动性，且血糖测定受到许多因素影响，因此入院时即刻血糖并不能全面反映患者在住院期间的整体血糖状