氯米芬联合二甲双胍治疗多囊卵巢综合征的效果分析.docVIP

氯米芬联合二甲双胍治疗多囊卵巢综合征的效果分析 　　[摘要] 目的 探讨氯米芬联合二甲双胍治疗多囊卵巢综合征的效果。 方法 选取2011年2月～2014年2月本院收治的60例多囊卵巢综合征患者作为研究对象，随机分为观察组和对照组。观察组给予二甲双胍和氯米芬治疗，对照组给予氯米芬治疗。比较两组的血清雌二醇、黄体生成素、睾酮水平，并观察两组的妊娠情况。 结果 观察组的血清雌二醇水平显著低于对照组，差异有统计学意义（P0.05）。观察组的成熟卵泡数显著低于对照组，差异有统计学意义（P0.05）。观察组的妊娠率显著高于对照组，差异有统计学意义（P0.05）。 结论 氯米芬联合二甲双胍治疗多囊卵巢综合征效果显著，能够改善患者的排卵状况，提高妊娠率。 　　[关键词] 多囊卵巢综合征；氯米芬；二甲双胍 　　[中图分类号] R711.75 [文献标识码] A [文章编号] 1674-4721（2015）06（a）-0127-03 　　Effect analysis of clomiphene combined with metformin in the treatment of polycystic ovary syndrome 　　JING Li-hua 　　Department of Gynaecology，People′s Hospital of Tanghe County in Henan Province，Tanghe 473400，China 　　[Abstract] Objective To explore the effect of clomiphene combined with metformin in the treatment of polycystic ovary syndrome. Methods 60 cases with polycystic ovary syndrome from February 2011 to February 2014 in our hospital were selected and randomly divided into the observation group and the control group.The observation group was given metformin and clomiphene，the control group was given clomiphene.The level of serum estradiol，luteinizing hormone，testosterone in two groups was compared.The rate of pregnancy in two groups was observed. Results The level of serum estradiol in the observation group was lower than that in the control group，with significant difference（P0.05）.the number of mature follicles in the observation group was lower than that in the control group，with significant difference（P0.05）.The pregnancy rate in the observation group was higher than that in the control group，with significant difference（P0.05）. Conclusion The effect of clomiphene combined with metformin in the treatment of polycystic ovary syndrome is significant，which can improve the ovulation in the patients with polycystic ovary syndrome ovulation，and improve the pregnancy rate. 　　[Key words] Polycystic ovary syndrome；Clomiphene；Metformin 　　多囊卵巢综合征是育龄妇女阶段常见的内分泌系统疾病，主要表现为闭经、月经量少、不孕、多毛等症状，严重影响患者的身心健康和生活质量。有效的治疗能够提高多囊卵巢综合征的妊娠率，改善其生活质量，因此多囊卵巢综合征治疗措施的探讨成为