痴呆语言特点及及美金刚的有效治疗课件.pptVIP

* The Alzheimer‘s Disease Assessment Scale-Cognitive Subscale (ADAS-cog) is an 11 item scale assessing cognitive domains of memory, language, orientation, reasoning, and praxis. The scores range from 0 to 70 with lower scores indicating less impairment. This slide depicts the mean change in ADAS-cog (? SEM) score from baseline over 24 weeks of treatment with either memantine (20mg/day) or placebo.The data analysis is based on the observed cases (OC). Additionally the endpoint was also analyzed based on the intent-to-treat (ITT) population using the last observation carried forward (LOCF) metho