wavelet-baseddenoisingofcardiacpetimages.pptVIP

Cardiac PET Imaging A. Cuhadar, G. Green and R. deKemp Wavelet-based Denoising of Cardiac PET Data M.A.Sc. Thesis Geoffrey Green, B. Eng. Electrical Supervisors: Dr. Aysegul Cuhadar Carleton SCE Dr. Rob deKemp Cardiac PET Center, Ottawa Heart Institute Outline of Presentation Problem Statement / Thesis Motivation 1 Problem Statement / Thesis Motivation 2 Published Results Thesis Objective Thesis Contributions Background - Cardiac Anatomy Background - PET Background – PET in cardiology Background – Wavelets 1 Background – Wavelets 2 Background – Wavelet based denoising Spatially Adaptive Thresholding Spatially Adaptive Thresholding – 1D example Spatially Adaptive Thresholding – 1D example Cross Scale Regularization Cross Scale Regularization – 1D example Denoising Experiments Denoising Experiments Denoising Experiments Selected Results - Phantom Selected Results – Static Clinical Data Selected Results – Dynamic Clinical Data Future Work Denoising GUI Wavelet-based Denoising of Cardiac PET Data M.A.Sc. Thesis Geoffrey Green, B. Eng. Electrical Supervisors: Dr. Aysegul Cuhadar Carleton SCE Dr. Rob deKemp Cardiac PET Center, Ottawa Heart Institute * January 11, 2005 Problem Statement / Thesis Motivation Thesis Objective Thesis Contributions / Publications Background Information Cardiac anatomy PET and its use in cardiology Wavelets and wavelet-based denoising Spatially Adaptive Thresholding Cross Scale Regularization Denoising Experiments Representative Results Future Work PET images of the heart using 82Rb radiotracer are performed to observe and quantify uptake of blood flow to the heart muscle. Such myocardial perfusion measures can be used to diagnose coronary arterial disease and prescribe an appropriate treatment. 82Rb is used for several practical reasons: no on-site cyclotron required short half life 76s allows quick, repeated studies like potassium, selectively taken up in cardiac muscle tissue HOWEVER,