第三章蛋白质的分子设计修改概要.ppt

* * * * * * * * * * * * * * * * * * * * * Rop蛋白，哺乳动物突触融合蛋白的果蝇同系物，神经递质释放的重要调节蛋白。 * * * * * * * * * * * * * * * * * * * * * * * * * Ru:钌 (ruthenium) * * * * * * XLOGP: A New Atom-Addition Method for Calculating Partition Coefficients Renxiao Wang, Ying Fu, and Luhua Lai Institute of Physical Chemistry, Peking University J.Chem.Inf.Comput.Sci. 1997, 37, 615-621 Using 80 atom types (C, H, O, N, S, P, halogens) and 5 correction factors Correlation between the calculated logP values and the experimental values of 1831 organic compounds Molecular lipophilicity potential (MLP) of melatonin 文献阅读及讨论要