NMDA依赖的突触长时程增强和长时程抑制模型与仿真研究.docVIP

NMDA依赖的突触长时程增强和长时程抑制模型与仿真研究 作者：董爱荣，谭小丹，苏永春，高天明， 邓亲恺 【关键词】 长时程增强 A model and simulation research of NMDAdepended bidirectional synaptic plasticit 【Astract】 AIM: To study the correlative mechanism between the induction of long term modification and the activity of different NMDA receptor subtypes. METHODS: Based on the analysis of dynamic properties of NMDA receptor subtypes, an amended mathematical model of postsynaptic calcium was proposed to describe the relationship between different NMDA receptor subtype activity and presyna