复方甘草酸苷联合复方氟米松软膏治疗慢性湿疹的临床效果观察.docVIP

复方甘草酸苷联合复方氟米松软膏治疗慢性湿疹的临床效果观察 　　 　　[摘要] 目的 观察复方甘草酸苷联合复方氟米松软膏治疗慢性湿疹的临床效果。 方法 选取2011年7月～2013年6月本科诊治的84例慢性湿疹患者为研究对象，将其随机分为对照组与治疗组各42例。对照组采用复方氟米松软膏外用治疗，治疗组在对照组的基础上加用复方甘草酸苷口服治疗，两组疗程均为4周。比较两组的临床疗效及不良反应。 结果 治疗组总有效率为92.86%，对照组总有效率为76.19%，治疗组明显优于对照组，差异有统计学意义（P＜0.05）。 结论 复方甘草酸苷联合复方氟米松软膏治疗慢性湿疹效果满意，值得临床推广应用。 　　[关键词] 复方甘草酸苷；复方氟米松软膏；慢性湿疹；临床疗效 　　[中图分类号] R758.23[文献标识码] A[文章编号] 1674-4721（2014）04（c）-0075-02 　　 　　Clinical curative effect observation of compound glycyrrhizin combined with compound flumetasone ointment in treatment of chronic eczema 　　LIN Qing 　　The Central Hospital of Yongzhou City in Hunan Province,Yongzhou 425000,China 　　[Abstract] Objective To observe the clinical curative effect of compound glycyrrhizin combined with compound flumetasone ointment in the treatment of chronic eczema.Methods 84 cases of patients with chronic eczema who were treated in our hospital from July 2011 to June 2013 were selected,and were randomly divided into control group and observation group.Control group (42 cases) were externally treated by compound flumetasone ointment,observation group (42 cases) were added with compound glycyrrhizin based on the control group′s treatment,the treatment period were 4 weeks.Results The total effective rate of treatment group was 92.86%,the control group was 76.19%,the treatment group was obviously better than that of the control group,the difference was significant (P0.05).Conclusion The effect of compound glycyrrhizin combined with compound flumetasone ointment in the treatment of chronic eczema is satisfactory,be worth to clinical application. 　　[Key Words] Compound glycyrrhizin;Compound flumetasone ointment;Chronic eczema;Clinical curative effect 　　湿疹临床上分为急性、亚急性和慢性湿疹。慢性湿疹常由急性、亚急性湿疹反复发作不愈迁延而来，亦可因挠抓、摩擦或其他刺激，起初即表现为慢性湿疹[1]。其临床症状主要为局限性，边缘清楚的皮损斑块。患处皮肤浸润肥厚，表面粗糙，呈暗红色或伴色素沉着[2]，临床就诊者皮损部位以手足、小腿、肘窝、乳房、外阴、肛门等处多见。慢性湿疹临床比较难治且易复发，因此起病之初即应及时治疗。我科采用复方甘草酸苷联合复方氟米松软膏治疗慢性湿疹，取得良好的临床效果。 　　1 资料与方法 　　1.1 一般资料 　　选取2011年7月～2013年6月我科诊治的84例慢性湿疹患者为研究对象，其中，男性45例，女性