醒脑静联合奥拉西坦治疗急性期脑出血疗效观察.docVIP

醒脑静联合奥拉西坦治疗急性期脑出血疗效观察 　　[摘要] 目的 观察醒脑静联合奥拉西坦治疗急性期脑出血的临床疗效及安全性。 方法 将200例急性期脑出血患者随机分为四组，每组50例。对照组只给予脑出血常规治疗，其他三组在给予常规治疗的基础上分别接受醒脑静治疗、奥拉西坦治疗、醒脑静联合奥拉西坦治疗。治疗14 d后进行疗效判定，并比较四组治疗前后神经功能缺损评分的变化。 结果 治疗总有效率：对照组74.0%，醒脑静组84.0%，奥拉西坦组86.0%，联合用药组96.0%，三组均高于对照组，而联合用药组最高，差异有显著性（P 0.05），三组治疗后神经功能缺损评分减少值均高于对照组（P 0.05）， 而联合用药组减少值最高，与醒脑静组及奥拉西坦组比较差异有显著性（P 0.05）。三组患者均未出现不良反应。 结论 醒脑静联合奥拉西坦治疗急性期脑出血，可促进血肿吸收及神经修复，显著改善患者的神经功能缺损等临床症状，疗效确切，安全可靠。 　　[关键词] 醒脑静；奥拉西坦；联合； 脑出血；急性期 　　[中图分类号] R743.34 [文献标识码] B [文章编号] 1673-9701（2013）34-0083-02 　　The clinical efficacy of Xingnaojing injection combined with Oxiracetam injection in the treatment of acute cerebral hemorrhage 　　WU Yong LIANG Yan HUANG Dandan DENG Yaofang 　　Department of Neurology，the Peoples Hospital of Gaozhou City in Guangdong Province， Gaozhou 525200，China 　　[Abstract] Objective To observe the clinical efficacy and safety of Xingnaojing injection combined with Oxiracetam injection in the treatment of acute cerebral hemorrhage. Methods Two hundreds cases of patients with acute cerebral hemorrhage hospitalized in our hospital were randomly divided into 4 groups（n = 50）.Patients in control group were given conventional treatment for cerebral hemorrhage.On the basis of conventional treatment for cerebral hemorrhage，we used Xingnaojing injection，Oxiracetam injection，Xingnaojing injection combined with Oxiracetam injection separately to treate 3 treatment groups for 14 days. Results After treatment，the total effective rate of control group was 74.0%.It was 84.0% in the treatment group used Xingnaojing injection. It was 86.0% in the treatment group used Oxiracetam Injection.It was 96.0% in the combination group.The total effective rate of 3 treatment groups were higher than the control groups，and it was highest in the combination group，the difference was statistically significant（P 　　[Key words] Xingnaojing injection； Oxiracetam injection； Combination； Cerebral hemorrhage； Acute 　　脑出血（ICH）是临床上神经科常见的急性脑血管病，具有很高的病死率和病残率。脑出血后脑水肿是造成患者脑功