硝普钠联合多巴胺治疗顽固性心力衰竭的疗效分析.docVIP

硝普钠联合多巴胺治疗顽固性心力衰竭的疗效分析 　　[摘要] 目的 探讨硝普钠联合多巴胺治疗顽固性心力衰竭的临床疗效。方法 采用随机分组方法将90例患者分为治疗组和对照组，治疗组在常规综合治疗的基础上给予硝普钠联合多巴胺持续泵入治疗，对照组仅采用常规综合治疗。 结果 治疗组和对照组疗效总有效率分别为95.6%和66.7%，治疗组总有效率高于对照组，两组差异有统计学意义（P0.05）。 结论 在常规综合治疗的基础上应用硝普钠联合多巴胺治疗顽固性心力衰竭疗效显著，值得临床推广。 　　[关键词] 顽固性心力衰竭；硝普钠；多巴胺 　　[中图分类号] R541.6 [文献标识码] A [文章编号] 1674-4721（2013）11（a）-0088-02 　　Analysis on effect of sodium nitroprusside combined with dopamine in the treatment of intractable heart failure 　　ZHANG Xiao-ming 　　People′s Hospital of Dongguan City in Guangdong Province，Dongguan 523000，China 　　[Abstract] Objective To investigate the clinical effect of sodium nitroprusside combined with dopamine in the treatment of intractable heart failure. Methods 90 patients were divided into treatment group and control group using randomization method， patients in treatment group were treated by sodium nitroprusside combined with dopamine continuous pumping on the basis of conventional comprehensive treatment， while patients in control group were only treated by conventional comprehensive treatment. Results The total effective rate of treatment group and control group was 95.6% and 66.7% respectively， and the efficacy of treatment group was more significant than that of control group， the difference between the two groups was significant （P0.05）. Conclusion On the basis of conventional comprehensive treatment， the efficacy of sodium nitroprusside combined with dopamine in treatment of intractable heart failure is significant， it is worthy of clinical promotion. 　　[Key words] Intractable heart failure； Sodium nitroprusside； Dopamine 　　顽固性心力衰竭又称为难治性心力衰竭[1]，是心血管内科较为常见的临床综合征，是指经过各种治疗后病情未能得到改善或好转甚至恶化的心力衰竭[2]。随着人们生活方式的改变和人口老龄化的进展，其发病率、病死率亦在逐年上升，对人们的生命健康造成了严重威胁，因此，给予患者合理有效的治疗对提高患者的生存质量具有十分重要的意义。但是由于顽固性心力衰竭具有病情易反复、预后差等特点，致其临床治疗较为棘手[3]，是心血管医生面临的重大难题。近年来，本院在常规综合治疗的基础上采用硝普钠联合多巴胺持续泵入的方法治疗顽固性心力衰竭，取得了满意效果，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选择2011年1月～2013年1月本院诊治的顽固性心力衰竭患者90例，均符合《内科学》中顽固性心力衰竭的诊断标准[4]。采用随机分组方法将90例患者分为治疗组和对照组，各45例。治疗组中，男31例，女14例