Evaluation.docVIP

Evaluation of esophageal function in patients with esophageal motor abnormalities using multichannel intraluminal impedance esophageal manometry ? Yu Kyung Cho, Myung-Gyu Choi, Jae Myung Park, Jung Hwan Oh, Chang Nyol Paik, Joon Wook Lee, In Seok Lee, Sang Woo Kim, In-Sik Chung Catholic University of Korea, Seoul, Korea Correspondence to: Dr Myung-Gyu Choi, Department of Internal Medicine, The Catholic University of Korea, Kangnam St. Mary’s hospital, Banpodong 505, Seochogu, Seoul, Korea. choim@catholic.ac.kr Telephone: +82-2-5902471? Fax: +82-2-5902387 Received: 2005-11-03?????????Accepted: 2006-08-30 ? Abstract AIM: To evaluate the functional aspect of esophageal motility in healthy subjects and in patients who were referred for esophageal function testing using multichannel intraluminal impedance-esophageal manometry (MII-EM), and to assess the clinical utility of MII-EM. ? METHODS: From September 2003 to January 2004, we performed the MII-EM on healthy volunteers and all the patients who were referred for esophageal function testing. Each patient received 10 liquid and 10 viscous swallows. We analyzed the results, the impedance and the manometric findings. Some of the subjects had additional ambulatory 24-h pH study performed to diagnose gastroesophageal reflux disease (GERD). ? RESULTS: Among 89 studied subjects, the MII-EM findings showed normal esophageal motility in 50 (56.17%), ineffective esophageal motility (IEM) in 17 (19.10%), nutcracker esophagus in 7 (7.86%), achalasia in 4 (4.49%), and scleroderma esophagus in 11 (12.35%) cases. The completeness and the speed of bolus transit were in the order of nutcracker esophagus, normal manometry and IEM. Some of the swallows showing normal manometry and IEM had incomplete transit. In the achalasia and scleroderma esophagus, almost all the swallows had incomplete transit. The body amplitudes were higher for the swallows with complete transit than for the swallows with incomplete transit. There was not a sign