ppt课件-parkinson’stestdevicedevelopment.pptVIP

Parkinson’s Test Device Development Tiffany Feltman Erin Sikkel Parkinson’s Disease A disorder of the brain that occurs when the neurons in the substantia nigra die or become slightly impaired. These neurons usually produce the chemical dopamine which allows for smooth, coordinated functioning of the muscles in the body. Some of the main symptoms are tremors, slowness of movement, rigidity, and difficulty with balance. These problems can lead to a deeper state of the disease which includes small handwriting, stiff facial expression, shuffling walk, muffled speech, which all lead to depression. Parkinson’s Disease Affects 1.5 million Americans Affected after the age of 65, but roughly 15% are diagnosed under the age of 50. According to these demographics, the market size for this project is great. The market size for this product would be high since it will give a greater insight into the brain stimulation and allow doctors and researchers to find out more about the disease and how to treat it. Competition Activa Tremor Control System Delivered by an implanted medical device similar to cardiac pacemakers, that uses electrical stimulation to block the brain signals that cause tremors. Stimulates targeted cells in the thalamus through surgically implanted electrodes in the brain and are connected to a neurostimulator implanted near the collarbone. The electrical stimulation can be non-invasively adjusted to fit the patient’s needs. Competition Ventro-intermediate (Vim) nucleus of thalamus Common target for the treatment of tremors as it is suggested to play an important role in the occurrence of disease. By using conventional MR imaging, metabolic alterations of the contralateral thalamus can be seen. It reduces the tremors associated with Parkinson’s Disease, but unable to help with other symptoms Competition Pallidotomy The Globus pallidus is a pale-appearing spherical area in the brain. It is part of the lentiform nucleus, which is part of the s