吴茱萸穴位贴敷治疗冠心病低心率变异性的临床研究.docVIP

吴茱萸穴位贴敷治疗冠心病低心率变异性的临床研究 　　[摘要] 目的 探讨吴茱萸穴位贴敷在低心率变异性冠心病患者治疗中的应用价值，以指导临床治疗。 方法 选取2013年7月～2015年6月广东省深圳市宝安区中医院接诊的低心率变异性冠心病患者100例，应用随机数字表法将其分为观察组与对照组，每组50例。对照组患者接受美托洛尔在内的常规治疗，观察组患者在常规治疗的基础上进行吴茱萸穴位贴敷法。比较两组治疗前后心率变异率变化情况。 结果 入组时两组间24 h窦性R-R间期标准差（SDNN）、24 h连续5 min窦性R-R间期均值标准差（SDANN）、相邻窦性R-R间期差值均方根（RMSSD）、相邻窦性R-R间期差值超过50 ms的百分比（PNN50）、极低频功率（VLF）、低频功率（LF）及高频功率（HF）比较，差异均无统计学意义（P 0.05），而在完成2周治疗后，两组SDNN、SDANN、RMSSD、PNN50、VLF、LF及HF均明显升高，且观察组明显高于对照组，差异均有统计学意义（P 0.05）。 结论 吴茱萸穴位贴敷可显著改善低心率变异性冠心病患者的心率变异性。 　　[关键词] 吴茱萸；穴位贴敷；低心率变异性；冠心病 　　[中图分类号] R543.3 [文献标识码] A [文章编号] 1673-7210（2016）07（a）-0088-04 　　[Abstract] Objective To investigate the application value of Fructus Evodiae acupoint sticking therapy in coronary heart disease with low heart rate variability， so as to guide clinical treatment. Methods One hundred cases of coronary heart disease patients with low heart rate variability admitted to Baoan Hospital of Traditional Chinese Medicine in Shenzhen City from July 2013 to June 2015 were selected， and they were divided into the observation group and the control group by random number table， with 50 cases in each group. The control group received conventional treatment including Metoprolol， on basis of conventional therapy， the observation group was taken Fructus Evodiae acupoint sticking therapy. The changes of heart rate variability before and after treatment between the two groups were compared. Results The differences of 24 h standard diviation of NN intervals （SDNN）， 24 h continuous 5 min standard diviation of the average NN intervals （SDANN）， root mean square successive difference between adjacent normal RR intervals （RMSSD）， percent of difference between adjacent normal RR intervals that was longer than or equal to 50 ms （PNN50）， very low frequency （VLF）， low frequency （LF） and high frequency （HF） of the two groups at admission were not statistically significant （P 0.05）. Two weeks after completing the treatment， the SDNN， SDANN， RMSSD， PNN50， VLF， LF and HF in both gro