颅脑损伤后认知功能障碍特点与损伤部位相关性研究.docVIP

颅脑损伤后认知功能障碍特点与损伤部位相关性研究 　　[摘要] 目的 探讨颅脑损伤后认知功能障碍的特点与损伤部位的关系。 方法 根据蒙特利尔认知评估量表（MoCA）将106例颅脑损伤患者分为无认知功能障碍组（n=42）与认知功能障碍组（n=64），比较两组MoCA各认知域评分，并分析认知功能障碍患者不同损伤部位与MoCA各认知域评分的关系。 结果 认知功能障碍组除命名与定向力评分与无认知功能障碍组无明显差异外，其余如视空间与执行、语言、注意力、抽象能力、计算力及延迟记忆等评分均低于无认知功能障碍组，差异有高度统计学意义（P0.01）。损伤部位在额叶、颞叶及基底节的颅脑损伤患者认知功能障碍相对严重，主要表现在视空间与执行、计算力及延迟记忆障碍，与枕叶、顶叶损伤患者比较差异有统计学意义（P0.05）。 结论 额叶、颞叶及基底节损伤的患者一般认知功能障碍更为严重，临床应对这类患者引起足够的重视。 　　[关键词] 颅脑损伤；认知功能障碍；特点；损伤部位 　　[中图分类号] R739.41 [文献标识码] B [文章编号] 1673-9701（2016）23-0071-03 　　[Abstract] Objective To research the relationship between the characteristic of cognitive dysfunction after craniocerebral trauma and the trauma position. Methods 106 cases with Craniocerebral trauma were divided into non-cognitive dysfunction group（n=42） and cognitive dysfunction group（n=64）according to the results of the MoCA，the MoCAs cognitive domain scores of two groups were compared，and the relationship between different trauma positions and MoCAs cognitive domain scores were analyzed. Results The scores of visual-spatial and executive function，language，attention，abstract，calculation and delayed memory of the cognitive dysfunction group were less than those of the non-cognitive dysfunction group except naming and directional force，the difference was statistically significant（P0.01）. The cognitive dysfunction patients with trauma in temporal lobe，frontal lobe and basal ganglia were more severe，mainly displays in visual-spatial and executive function，calculation and delayed memory，and compared with the patients with occipital lobe，parietal lobe in terms of cognitive dysfunction，the difference was statistically significant （P0.05）. Conclusion The patients with trauma in frontal lobe，basal ganglia and temporal lobe generally are more severe in terms of cognitive dysfunction，and it is necessary to pay more attention to such patients. 　　[Key words] Craniocerebral trauma； Cognitive dysfunction； Characteristic； Trauma position 　　创伤性颅脑损伤后多会伴发认知功能障碍，且不少数认知功能障碍持续时间比较长久，据了解，这种几率在轻