分子肿瘤病理学及转化研究的新进展.docVIP

??????????????分子肿瘤病理学及转化研究的新进展 [课程介绍] 本课程的授课目标是为学生提供通过转化医学深入了解分子肿瘤病理学的途径和方法。授课内容将涉及多个肿瘤研究领域的新进展，如miRNA, 肿瘤表观遗传学, 上皮间质转化，肿瘤干细胞，新的癌基因和抑癌基因等。分子肿瘤病理学与传统肿瘤病理学不但相辅相成,而且能在传统肿瘤病理学的基础上进一步发现新的肿瘤标志物用于早期检测，预测肿瘤的生物学行为及指导治疗。 本课程中将会讨论介绍多种分子生物学和病理学技术。例如FISH, 图象分析, 定量PCR 和多种基于 PCR 的突变分析,和病理免疫组织化学的标准实验流程和结果解读等。 本课程将鼓励学生运用转化医学的视点将基础分子病理学和临床研究进行整合分析。 本课程将进行13次授课，涉及分子肿瘤病理学和相关转化医学的多个前沿话题。 所有授课题目和授课教师请见附表. [课程特色] 特色1：前沿性和交叉性。 特色2：桥梁性（注重基础和临床研究的整合） 特色3：全部授课教师均有出国学习经历 Advances in Molecular Oncologic Pathology and Translational Research [Description] The goal of this course is providing new insights into molecular oncologic pathology through translational research involving multiple cancer research filed, such as miRNA, Epigenetics, Epithelial mesenchymal transition, cancer stem cells, novel oncogenes and tumor suppressor genes etc. Complementary to and based on traditional diagnostic pathology, molecular oncologic pathology can serve to identify the novel biomarker for early detection of cancer, predict the biological behavior of a given tumor and also guides the cancer therapy. Multiple molecular biology and pathology techniques will be discussed in this course including: FISH, image analysis, quantitative PCR and RT-PCR and a variety of PCR based mutational analyses, and standard flowchart and result interpretation for immunohistochemistry. This course should encourage students to develop a translational approach view to link basic molecular pathology and clinical based cancer study. In the body of the course, a series of 13 lectures will cover a wide range of advanced topics on translational research in molecular pathology. All lecture topics and lecturers are attached below (Table 1). [Features] Feature 1: Cross-cutting and Cutting-edge Feature 2: A bridging research linking basic and clinical science Feature 3: All lecturers with study abroad experience