222 cases of bilateral primary breast cancer prognostic factors.docVIP

 PAGE \* MERGEFORMAT 28 222 cases of bilateral primary breast cancer prognostic factors 【Abstract】 Objective To study the bilateral primary breast cancer (Bilateral Primary Breast Cancer, BPBC) and its prognostic factors. Methods of Tianjin Medical University Cancer Hospital in March 1972 ~ December 2003 admitted to 222 BPBC clinical data of patients with prognostic factor analysis. Results BPBC The 5,10-year cumulative survival rates were 78.73%, 69.09%. sBPBC the overall survival rates compared with mBPBC difference, but no statistical significance. The first side of node-positive result, and the second side of node-positive result, and the second side of tumor size, histological grading of the second side of the role of survival was statistically significant. Conclusion At the same time and the survival rate of metachronous BPBC similar. The second side of tumor ≥ 5cm, bilateral lymph node-positive poor prognosis. Multivariate analysis showed that the second side of tumor size and the first side, second side with lymph node-positive factors influencing the prognosis. Keywords: bilateral primary breast cancer; prognosis; survival rate Prognostic of 222 Cases Bilateral Primary Breast Cancer Abstract: Objective To evaluate the outcome and prognosis analyze of bilateral primary breast cancer (BPBC). Methods The clinical data of 222 patients with BPBC, admitted to Tianjin Medical University Cancer Institute and Hospital from March 1972 to December 2003 were collected and analyzed on prognosis factors. Results 5  year and 10  year Cumulative Survival rate of BPBC were 78.73% and 69.09%. Cumulative Survival rate of sBPBC (Synchronous BPBC, sBPBC) is lower than mBPBC’s (Metachronous BPBC, mBPBC), but there is no significant difference . The status of bilateral lymph node of and tumor size of secondary cancer affect the survival of BPBC significantly. Conclusion The survival rate of sBPBC is similar to that of mBPBC. The prognosis of pat